Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5TC01 | ATP1A1 | ATPase Na+/K+ transporting subunit alpha … | Homo sapiens (Human) | 144 aa |
Protein Details: Q5TC01 (ATP1A1)
Protein Information
| Accession | Q5TC01 |
|---|---|
| Protein Names | ATPase Na+/K+ transporting subunit alpha 1 |
| Gene Symbol | ATP1A1 |
| Organism | Homo sapiens (Human) |
| Length | 144 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 29575903 31251020 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MDELKKEVSM11DDHKLSLDEL21HRKYGTDLSR31GLTSARAAEI41LARDGPNALT
51-10051PPPTTPEWIK61FCRQLFGGFS71MLLWIGAILC81FLAYSIQAAT91EEEPQNDNLY
101-144101LGVVLSAVVI111ITGCFSYYQE121AKSSKIMESF131KNMVPQQALV141IRNG
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | - | - |
cerebral cortex
(36430497)
|
GPS-Palm: 0.81
Deep-Palm: 0.86
|
|
| 80 | - | - | - |
Deep-Palm: 0.66
|
|
| 114 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.93
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.444
4
cerebral cortex
Specificity: 0.444
4/4 (100.0%)
3
LNCaP
Specificity: 0.333
3/3 (100.0%)
1
HeLa cell
Specificity: 0.111
1/1 (100.0%)
1
Jurkat T cell
Specificity: 0.111
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 93 | C → W | 0.002288 | SNP | Missense Mutation | STAD |
| 229 | P → _D230insTLPSLCWYTN | 0.002294 | INS | In Frame Ins | OV |
| 310 | S → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 326 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 343 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 459 | C → Vfs*36 | 0.002747 | INS | Frame Shift Ins | LIHC |
| 518 | C → Y | 0.001014 | SNP | Missense Mutation | BRCA |
| 755 | F → C | 0.002288 | SNP | Missense Mutation | STAD |
| 766 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| ? | ? → ? | 0.001887 | SNP | Missense Mutation | UCEC |