Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5TFE4 | NT5DC1 | 5'-nucleotidase domain-containing protein 1 (EC … | Homo sapiens (Human) | 455 aa |
Protein Details: Q5TFE4 (NT5DC1)
Protein Information
| Accession | Q5TFE4 |
|---|---|
| Protein Names | 5'-nucleotidase domain-containing protein 1 (EC 3.1.3.-) |
| Gene Symbol | NT5DC1 |
| Organism | Homo sapiens (Human) |
| Length | 455 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAQHFSLAAC11DVVGFDLDHT21LCRYNLPESA31PLIYNSFAQF41LVKEKGYDKE
51-10051LLNVTPEDWD61FCCKGLALDL71EDGNFLKLAN81NGTVLRASHG91TKMMTPEVLA
101-150101EAYGKKEWKH111FLSDTGMACR121SGKYYFYDNY131FDLPGALLCA141RVVDYLTKLN
151-200151NGQKTFDFWK161DIVAAIQHNY171KMSAFKENCG181IYFPEIKRDP191GRYLHSCPES
201-250201VKKWLRQLKN211AGKILLLITS221SHSDYCRLLC231EYILGNDFTD241LFDIVITNAL
251-300251KPGFFSHLPS261QRPFRTLEND271EEQEALPSLD281KPGWYSQGNA291VHLYELLKKM
301-350301TGKPEPKVVY311FGDSMHSDIF321PARHYSNWET331VLILEELRGD341EGTRSQRPEE
351-400351SEPLEKKGKY361EGPKAKPLNT371SSKKWGSFFI381DSVLGLENTE391DSLVYTWSCK
401-450401RISTYSTIAI411PSIEAIAELP421LDYKFTRFSS431SNSKTAGYYP441NPPLVLSSDE
451-455451TLISK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | HAD-like superfamily | - |
Unknown
(32651440)
|
Deep-Palm: 0.02
|
|
| 22 | HAD-like superfamily HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase | - |
Unknown
(32651440)
|
Deep-Palm: 0.64
|
|
| 62 | - | - | - |
Deep-Palm: 0.84
|
|
| 63 | - | - | - |
Deep-Palm: 0.80
|
|
| 119 | - | - | - |
Deep-Palm: 0.16
|
|
| 139 | - | - | - |
Deep-Palm: 0.37
|
|
| 179 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.40
|
|
| 197 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.92
|
|
| 226 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.74
|
|
| 230 | - | - | - |
Deep-Palm: 0.20
|
|
| 399 | - | - | - |
Deep-Palm: 0.84
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
293T cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 10 | C → C | 0.001887 | SNP | Silent | UCEC |
| 63 | C → Ifs*9 | 0.001969 | INS | Frame Shift Ins | HNSC |
| 63 | C → Nfs*17 | 0.002427 | INS | Frame Shift Ins | BLCA |
| 323 | R → C | 0.002288 | SNP | Missense Mutation | STAD |