Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5TYX0 | PRAMEF5; PRAMEF23; PRAMEF5L | PRAME family member 5 | Homo sapiens (Human) | 476 aa |
Protein Details: Q5TYX0 (PRAMEF5)
Protein Information
| Accession | Q5TYX0 |
|---|---|
| Protein Names | PRAME family member 5 |
| Gene Symbol | PRAMEF5; PRAMEF23; PRAMEF5L |
| Organism | Homo sapiens (Human) |
| Length | 476 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSIRTPPRLL11ELAGRSLLRD21QALAMSTLEE31LPTELFPPLF41MEAFSRRRCE
51-10051ALKLMVQAWP61FRRLPLRPLI71KMPCLEAFQA81VLDGLDALLT91QGVHPRRWKL
101-150101QVLDLQDVCE111NFWMVWSEAM121AHGCFLNAKR131NKKPVQDCPR141MRGQQPLTVF
151-200151VELWLKNRTL161DEYLTCLLLW171VKQRKDLLHL181CCKKLKILGM191PFRNIRSILK
201-250201MVNLDCIQEV211EVNCKWVLPI221LTQFTPYLGH231MRNLQKLVLS241HMDVSRYVSP
251-300251EQKKEIVTQF261TTQFLKLCCL271QKLSMNSVSF281LEGHLDQLLS291CLKTSLKVLT
301-350301ITNCVLLESD311LKHLSQCPSI321SQLKTLDLSG331IRLTNYSLVP341LQILLEKVAA
351-400351TLEYLDLDDC361GIIDSQVNAI371LPALSRCFEL381NTFSFCGNPI391SMATLENLLS
401-450401HTIILKNLCV411ELYPAPRESY421DADGTLCWSR431FPQIRAELMK441RVRDLRHPKR
451-476451ILFCTDCCPD461CGNRSFYDLE471ADQCCC
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 49 | Prediction (Medium) | - | - |
| 74 | Prediction (Medium) | - | - |
| 124 | Prediction (Medium) | - | - |
| 138 | Prediction (Medium) | - | - |
| 166 | Prediction (High) | - | - |
| 181 | CYSMODDB SWISSPALM DBPTM Prediction (High) | - | - |
| 182 | CYSMODDB SWISSPALM DBPTM Prediction (Medium) | - | - |
| 206 | Prediction (Medium) | - | - |
| 214 | Prediction (Low) | - | - |
| 268 | Prediction (High) | - | - |
| 269 | Prediction (High) | - | - |
| 291 | Prediction (Medium) | - | - |
| 304 | Prediction (Medium) | - | - |
| 317 | Prediction (Low) | - | - |
| 409 | Prediction (Low) | - | - |
| 454 | Prediction (High) | - | - |
| 457 | Prediction (High) | - | - |
| 458 | Prediction (Medium) | - | - |
| 474 | Prediction (High) | - | - |
| 475 | Prediction (High) | - | - |
| 476 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 109 | C → Y | 0.002427 | SNP | Missense Mutation | BLCA |
| 109 | C → Y | 0.001887 | SNP | Missense Mutation | UCEC |
| 166 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 458 | C → F | 0.003460 | SNP | Missense Mutation | CESC |
| 474* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |