Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5VST6-2 | ABHD17B | Alpha/beta hydrolase domain-containing protein 17B … | Homo sapiens (Human) | 288 aa |
Protein Details: Q5VST6-2 (ABHD17B)
Protein Information
| Accession | Q5VST6-2 |
|---|---|
| Protein Names | Alpha/beta hydrolase domain-containing protein 17B (Abhydrolase domain-containing protein 17B) (EC 3.1.2.22) |
| Gene Symbol | ABHD17B |
| Organism | Homo sapiens (Human) |
| Length | 288 aa |
| Isoforms | |
| Related PMIDs | 31251020 32651440 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MNNLSFSELC11CLFCCPPCPG21KIASKLAFLP31PDPTYTLMCD41ESGSRWTLHL
51-10051SERADWQYSS61REKDAIECFM71TRTSKGNRIA81CMFVRCSPNA91KYTLLFSHGN
101-150101AVDLGQMSSF111YIGLGSRINC121NIFSYDYSGY131GASSGKPTEK141NLYADIEAAW
151-200151LALRTRYGIR161PENVIIYGQS171IGTVPSVDLA181ARYESAAVIL191HSPLTSGMRV
201-250201AFPDTKKTYC211FDAFPNIDKI221SKITSPVLII231HGTEDEVIDF241SHGLALFERC
251-288251QRPVEPLWVE261GAGHNDVELY271GQYLERLKQF281VSQELVNL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 10 | - | - | - |
Deep-Palm: 0.03
|
|
| 11 | - | - | - |
Deep-Palm: 0.04
|
|
| 14 | - | - | - |
Deep-Palm: 0.52
|
|
| 15 | - | - | - |
Deep-Palm: 0.64
|
|
| 18 | - | - | - |
Deep-Palm: 0.83
|
|
| 39 | - | - | - |
Deep-Palm: 0.85
|
|
| 68 | - | - | - |
Deep-Palm: 0.47
|
|
| 81 | - | - | - |
Deep-Palm: 0.45
|
|
| 86 | - | - | - |
Deep-Palm: 0.70
|
|
| 120 | - | - | - |
Deep-Palm: 0.26
|
|
| 210 | - | - | - |
Deep-Palm: 0.57
|
|
| 250 | - | - | - |
Deep-Palm: 0.86
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
4
LNCaP
Specificity: 0.364
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.364
4/4 (100.0%)
2
PC3
Specificity: 0.182
2/2 (100.0%)
1
Jurkat T cell
Specificity: 0.091
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 45 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 120 | C → S | 0.001764 | SNP | Missense Mutation | LUAD |
| 127 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 167 | Y → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 168 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 243 | G → C | 0.001764 | SNP | Missense Mutation | LUAD |