Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5VVL7 | DBT | Dihydrolipoamide acetyltransferase component of pyruvate … | Homo sapiens (Human) | 320 aa |
Protein Details: Q5VVL7 (DBT)
Protein Information
| Accession | Q5VVL7 |
|---|---|
| Protein Names | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex (EC 2.3.1.-) |
| Gene Symbol | DBT |
| Organism | Homo sapiens (Human) |
| Length | 320 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 32651440 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.905
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
38
LNCaP cells
Specificity: 0.905
38/46 (82.6%)
2
PC3 cells
Specificity: 0.048
2/4 (50.0%)
1
Jurkat T cells
Specificity: 0.024
1/25 (4.0%)
1
Cerebral cortex
Specificity: 0.024
1/4 (25.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAAVRMLRTW11SRNAGKLICV21RYFQTCGNVH31VLKPNYVCFF41GYPSFKYSHP
51-10051HHFLKTTAAL61RGQVVQFKLS71DIGEGIREVT81VKEWYVKEGD91TVSQFDSICE
101-150101VQSDKASVTI111TSRYDGVIKK121LYYNLDDIAY131VGKPLVDIET141EALKDSEEDV
151-200151VETPAVSHDE161HTHQEIKGRK171TLATPAVRRL181AMENNIKLSE191VVGSGKDGRI
201-250201LKEDILNYLE211KQTGAILPPS221PKVEIMPPPP231KPKDMTVPIL241VSKPPVFTGK
251-300251DKTEPIKGFQ261KAMVKTMSAA271LKIPHFGYCD281EIDLTELVKL291REELKPIAFA
301-320301RGIKLSFMPF311FLKYYFSWKS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 19 | Prediction (Medium) | - | - |
| 26 | Prediction (Medium) | - | - |
| 38 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 61 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 462 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |