Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q5VXH4 | PRAMEF6 | PRAME family member 6 | Homo sapiens (Human) | 476 aa |
Protein Details: Q5VXH4 (PRAMEF6)
Protein Information
| Accession | Q5VXH4 |
|---|---|
| Protein Names | PRAME family member 6 |
| Gene Symbol | PRAMEF6 |
| Organism | Homo sapiens (Human) |
| Length | 476 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSIRTPPRLL11ELAGRSLLRD21QALAMSTLEE31LPTELFPPLF41MEAFSRRRCE
51-10051ALKLMVQAWP61FRRLPLRPLI71KMPCLEAFQA81VLDGLDALLT91QGVHPRRWKL
101-150101QVLDLQDVCE111NFWMVWSEAM121ARGCFLNAKR131NKTPVQDCPR141MRGQQPLTVF
151-200151VELWLKNRTL161DEYLTCLLLW171VKQRKDLLHL181CCKKLKILGM191PFRNIRSILK
201-250201MVNLDCIQEV211EVNCKWVLPI221LTQFTPYLGH231MRNLQKLVLS241HMDVSRYVSP
251-300251EQKKEIVTQF261TTQFLKLCCL271QKLSMNSVSF281LEGHLDQLLS291CLKTSLKVLT
301-350301ITNCVLLESD311LKHLSQCPSI321SQLKTLDLSG331IRLTNYSLVP341LQILLEKVAA
351-400351TLEYLDLDDC361GIIDSQVNAI371LPALSRCFEL381NTFSFCGNPI391SMATLENLLS
401-450401HTIILKNLCV411ELYPAPRESY421DADGTLCWSR431FAQIRAELMK441RVRDLRHPKR
451-476451ILFCTDCCPD461CGNRSFYDLE471ADQCCC
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 49 | - | - | - |
GPS-Palm: 0.80
Deep-Palm: 0.95
|
|
| 74 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.98
|
|
| 109 | - | - | - |
Deep-Palm: 0.29
|
|
| 124 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.15
|
|
| 138 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.71
|
|
| 166 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.96
|
|
| 181 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.89
|
| 182 | SWISSPALM DBPTM CYSMODDB | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.94
|
| 206 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.83
|
|
| 214 | - | - | - |
GPS-Palm: 0.66
Deep-Palm: 0.63
|
|
| 268 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.75
|
|
| 269 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.77
|
|
| 291 | - | - | - |
GPS-Palm: 0.79
Deep-Palm: 0.97
|
|
| 304 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.95
|
|
| 317 | - | - | - |
GPS-Palm: 0.69
Deep-Palm: 0.95
|
|
| 360 | - | - | - |
Deep-Palm: 0.95
|
|
| 377 | - | - | - |
Deep-Palm: 0.73
|
|
| 386 | - | - | - |
Deep-Palm: 0.89
|
|
| 409 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.71
|
|
| 427 | - | - | - |
Deep-Palm: 0.96
|
|
| 454 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.14
|
|
| 457 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.16
|
|
| 458 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.06
|
|
| 461 | - | - | - |
Deep-Palm: 0.03
|
|
| 474 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
|
| 475 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 476 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 360 | C → F | 0.001887 | SNP | Missense Mutation | UCEC |
| 458 | C → F | 0.003460 | SNP | Missense Mutation | CESC |
| 458 | C → Y | 0.001969 | SNP | Missense Mutation | LGG |
| 474* | C → ? | 0.001887 | SNP | Nonsense Mutation | UCEC |