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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q60648 Gm2a Ganglioside GM2 activator (Cerebroside sulfate … Mus musculus (Mouse) 193 aa

Protein Details: Q60648 (Gm2a)

Protein Information
AccessionQ60648
Protein NamesGanglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3)
Gene SymbolGm2a
OrganismMus musculus (Mouse)
Length193 aa
IsoformsNo isoforms
Related PMIDs 31772009 35477839
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MHRLPLLLLL11GLLLAGSVAP21ARLVPKRLSQ31LGGFSWDNCD41EGKDPAVIKS
51-10051LTIQPDPIVV61PGDVVVSLEG71KTSVPLTAPQ81KVELTVEKEV91AGFWVKIPCV
101-150101EQLGSCSYEN111ICDLIDEYIP121PGESCPEPLH131TYGLPCHCPF141KEGTYSLPTS
151-193151NFTVPDLELP161SWLSTGNYRI171QSILSSGGKR181LGCIKIAASL191KGR
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
39 GM2-AP, lipid-recognition domain superfamily - -
Deep-Palm: 0.96
99 - - -
Deep-Palm: 0.60
106 - - -
Deep-Palm: 0.07
112 - - -
Deep-Palm: 0.12
125 - - -
Deep-Palm: 0.05
136 - - -
Deep-Palm: 0.50
138 - - -
Deep-Palm: 0.25
183 - - -
GPS-Palm: 0.95
Deep-Palm: 0.52
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Testis
Specificity: 0.667
2/2 (100.0%)
1
NSC
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine