Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q60930 Vdac2 Non-selective voltage-gated ion channel VDAC2 … Mus musculus (Mouse) 295 aa

Protein Details: Q60930 (Vdac2)

Protein Information
AccessionQ60930
Protein NamesNon-selective voltage-gated ion channel VDAC2 (VDAC-2) (mVDAC2) (Outer mitochondrial membrane protein porin 2) (Voltage-dependent anion-selective channel protein 6) (VDAC-6) (mVDAC6)
Gene SymbolVdac2
OrganismMus musculus (Mouse)
Length295 aa
IsoformsNo isoforms
Related PMIDs 28526873 29575903 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAECCVPVCP11RPMCIPPPYA21DLGKAARDIF31NKGFGFGLVK41LDVKTKSCSG
51-10051VEFSTSGSSN61TDTGKVSGTL71ETKYKWCEYG81LTFTEKWNTD91NTLGTEIAIE
101-150101DQICQGLKLT111FDTTFSPNTG121KKSGKIKSAY131KRECINLGCD141VDFDFAGPAI
151-200151HGSAVFGYEG161WLAGYQMTFD171SAKSKLTRSN181FAVGYRTGDF191QLHTNVNNGT
201-250201EFGGSIYQKV211CEDFDTSVNL221AWTSGTNCTR231FGIAAKYQLD241PTASISAKVN
251-295251NSSLIGVGYT261QTLRPGVKLT271LSALVDGKSF281NAGGHKLGLA291LELEA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 -
brain (39008777)
Liver (37925639)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.96
Deep-Palm: 0.01
5 -
brain (39008777)
Liver (37925639)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.94
Deep-Palm: 0.01
9 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Liver (37925639)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.02
14 Porin domain superfamily
brain (39008777)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.33
48 SWISSPALM DBPTM CYSMODDB Eukaryotic porin/Tom40 Eukaryotic porin Porin domain superfamily
Brain (31311849)
Liver (28526873)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.96
77 SWISSPALM DBPTM CYSMODDB Eukaryotic porin
Brain (31311849)
Liver (28526873)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.88
104 SWISSPALM DBPTM CYSMODDB Eukaryotic porin
Brain (31311849)
Forebrain (28680068)
brain (39008777)
Liver (28526873)
Liver (34884899)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.92
134 - - -
Deep-Palm: 0.78
139 - - -
Deep-Palm: 0.69
211 Eukaryotic porin
Brain (34200797)
Brain (31311849)
Deep-Palm: 0.59
228 Eukaryotic porin
Brain (34200797)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.95
Deep-Palm: 0.88
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
6
Liver
Specificity: 0.094
6/6 (100.0%)
5
Brain
Specificity: 0.078
5/5 (100.0%)
2
Raw 264.7
Specificity: 0.031
2/2 (100.0%)
2
Testis
Specificity: 0.031
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.837
41
Brain tissue (Mass)
Specificity: 0.641
41/56 (73.2%)
8
Liver tissue (Mass)
Specificity: 0.125
8/8 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine