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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q60991 Cyp7b1 Cytochrome P450 7B1 (24-hydroxycholesterol 7-alpha-hydroxylase) … Mus musculus (Mouse) 507 aa

Protein Details: Q60991 (Cyp7b1)

Protein Information
AccessionQ60991
Protein NamesCytochrome P450 7B1 (24-hydroxycholesterol 7-alpha-hydroxylase) (EC 1.14.14.26) (25/26-hydroxycholesterol 7-alpha-hydroxylase) (EC 1.14.14.29) (3-hydroxysteroid 7-alpha hydroxylase) (Hippocampal transcript 1 protein) (HCT-1) (Oxysterol 7-alpha-hydroxylase)
Gene SymbolCyp7b1
OrganismMus musculus (Mouse)
Length507 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQGATTLDAA11SPGPLALLGL21LFAATLLLSA31LFLLTRRTRR41PREPPLIKGW
51-10051LPYLGMALKF61FKDPLTFLKT71LQRQHGDTFT81VFLVGKYITF91VLNPFQYQYV
101-150101TKNPKQLSFQ111KFSSRLSAKA121FSVKKLLTDD131DLNEDVHRAY141LLLQGKPLDA
151-200151LLETMIQEVK161ELFESQLLKI171TDWNTERIFA181FCGSLVFEIT191FATLYGKILA
201-250201GNKKQIISEL211RDDFFKFDDM221FPYLVSDIPI231QLLRNEESMQ241KKIIKCLTSE
251-300251KVAQMQGQSK261IVQERQDLLK271RYYRHDDPEI281GAHHLGFLWA291SLANTIPAMF
301-350301WAMYYILRHP311EAMEALRDEI321DSFLQSTGQK331KGPGISVHFT341REQLDSLVCL
351-400351ESTILEVLRL361CSYSSIIREV371QEDMNLSLES381KSFSLRKGDF391VALFPPLIHN
401-450401DPEIFDAPKE411FRFDRFIEDG421KKKSTFFKGG431KKLKTYVMPF441GLGTSKCPGR
451-500451YFAVNEMKLL461LIMLLTYFDL471EIIDRKPIGL481NHSRMFLGIQ491HPDSAVSFRY
501-507501KAKSWRS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
182 - - -
Deep-Palm: 0.59
246 - - -
Deep-Palm: 0.71
349 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Liver (34884899)
Deep-Palm: 0.96
361 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.95
447 - - -
Deep-Palm: 0.86
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Liver
Specificity: 1.000
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine