Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q61153 | Dio1 | Type I iodothyronine deiodinase (EC … | Mus musculus (Mouse) | 257 aa |
Protein Details: Q61153 (Dio1)
Protein Information
| Accession | Q61153 |
|---|---|
| Protein Names | Type I iodothyronine deiodinase (EC 1.21.99.3) (EC 1.21.99.4) (5DI) (DIOI) (Type 1 DI) (Type-I 5'-deiodinase) |
| Gene Symbol | Dio1 |
| Organism | Mus musculus (Mouse) |
| Length | 257 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLPQLWLWL11KRLVIFLQVA21LEVAVGKVLM31TLFPGRVKQS41ILAMGQKTGM
51-10051ARNPRFAPDN61WVPTFFSIQY71FWFVLKVRWQ81RLEDRAEFGG91LAPNCTVVCL
101-150101SGQKCNIWDF111IQGSRPLVLN121FGSCTUPSFL131LKFDQFKRLV141DDFASTADFL
151-200151IIYIEEAHAT161DGWAFKNNVD171IRQHRSLQER181VRAARLLLAR191SPQCPVVVDT
201-250201MQNQSSQLYA211ALPERLYVIQ221EGRICYKGKA231GPWNYNPEEV241RAVLEKLCTP
251-257251PRHVPQL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 95 | SWISSPALM DBPTM CYSMODDB | Iodothyronine deiodinase |
Liver
(28526873)
| - |
GPS-Palm: 0.90
Deep-Palm: 0.75
|
| 99 | SWISSPALM DBPTM CYSMODDB | Iodothyronine deiodinase |
Liver
(28526873)
| - |
Deep-Palm: 0.40
|
| 105 | - | - | - |
Deep-Palm: 0.74
|
|
| 124 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.91
|
|
| 194 | - | - |
Liver
(34884899)
|
Deep-Palm: 0.98
|
|
| 225 | - | - | - |
Deep-Palm: 0.97
|
|
| 248 | - | - | - |
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 0.714
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver tissue (Mass)
Specificity: 0.286
2/8 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.