Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q61316 | Hspa4 | Heat shock 70 kDa protein … | Mus musculus (Mouse) | 841 aa |
Protein Details: Q61316 (Hspa4)
Protein Information
| Accession | Q61316 |
|---|---|
| Protein Names | Heat shock 70 kDa protein 4 (Heat shock 70-related protein APG-2) |
| Gene Symbol | Hspa4 |
| Organism | Mus musculus (Mouse) |
| Length | 841 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29217618 29660268 29733200 34200797 34884899 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSVVGIDLGF11QSCYVAVARA21GGIETIANEY31SDRCTPACVS41FGPKNRSIGA
51-10051AAKSQVISNA61KNTVQGFKRF71HGRAFSDPFV81EAEKSNLAYD91IVQLPTGLTG
101-150101IKVTYMEEER111NFTTEQVTAM121LLSKLKETAE131SVLKKPVVDC141VVSVPSFYTD
151-200151AERRSVMDAT161QIAGLNCLRL171MNETTAVALA181YGIYKQDLPA191LEEKPRNVVF
201-250201VDMGHSAYQV211SVCAFNKGKL221KVLATAFDTT231LGGRKFDEVL241VNHFCEEFGK
251-300251KYKLDIKSKI261RALLRLSQEC271EKLKKLMSAN281ASDLPLSIEC291FMNDIDVSGT
301-350301MNRGKFLEMC311DDLLARVEPP321LRSVLEQSKL331KKEDIYAVEI341VGGATRIPAV
351-400351KEKISKFFGK361ELSTTLNADE371AVTRGCALQC381AILSPAFKVR391EFSITDVVPY
401-450401PISLRWNSPA411EEGLSDCEVF421PKNHAAPFSK431VLTFYRKEPF441TLEAYYSSPQ
451-500451DLPYPDPAIA461QFSVQKVTPQ471SDGSSSKVKV481KVRVNVHGIF491SVSSAALVEV
501-550501HKSEESEEPM511ETDQNAKEEE521KMQVDQEEPH531TEEQQQQPQT541PAENKAESEE
551-600551METSQAGSKD561KKTDQPPQAK571KAKVKTSTVD581LPIEHTLWQL591DREMLALYTE
601-650601NEGKMIMQDK611LEKERNDAKN621AVEEYVYEMR631DKLSGEYEKF641VSEDDRNTFT
651-700651LKLEDTENWL661YEDGEDQPKQ671VYVDKLAELK681SLGQPIKTRF691QESEERPKLF
701-750701EELGKQIQQY711MKVISSFKNK721EDQYEHLDAA731DVTKVEKSTN741EAMEWMNSKL
751-800751NLQNKQSLTV761DPVVKTKEIE771AKIKELTSIC781SPIISKPKPK791VEPPKEEPKH
801-841801AEQNGPVDGQ811GDNPGSQAAE821HGADTAVPSD831GDKKLPEMDI841D
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | ATPase, nucleotide binding domain Heat shock protein 70 family | - | - |
Deep-Palm: 0.89
|
|
| 34 | ATPase, nucleotide binding domain Heat shock protein 70 family |
MLE
(39008777)
| - |
Deep-Palm: 0.67
|
|
| 38 | ATPase, nucleotide binding domain Heat shock protein 70 family |
MLE
(39008777)
| - |
Deep-Palm: 0.82
|
|
| 140 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.95
|
|
| 167 | SWISSPALM DBPTM CYSMODDB | Hsp70 protein |
Liver
(28526873)
|
Brain
(35358180)
|
GPS-Palm: 0.90
Deep-Palm: 0.93
|
| 213 | - | - | - |
Deep-Palm: 0.65
|
|
| 245 | SWISSPALM DBPTM CYSMODDB | Hsp70 protein |
Forebrain
(28680068)
| - |
Deep-Palm: 0.93
|
| 270 | - | - | - |
Deep-Palm: 0.98
|
|
| 290 | - | - | - |
Deep-Palm: 0.70
|
|
| 310 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 376 | Hsp70 protein |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.81
|
|
| 380 | Hsp70 protein |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.78
|
|
| 417 | - |
brain
(39008777)
|
Brain
(35358180)
|
Deep-Palm: 0.86
|
|
| 780 | - |
Brain
(34200797)
|
Brain
(35358180)
|
GPS-Palm: 0.92
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
6
Liver
Specificity: 0.176
6/6 (100.0%)
5
Brain
Specificity: 0.147
5/5 (100.0%)
1
Raw 264.7
Specificity: 0.029
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
22
Brain tissue (Mass)
Specificity: 0.647
22/56 (39.3%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.