Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q61510 | Trim25 | E3 ubiquitin/ISG15 ligase TRIM25 (EC … | Mus musculus (Mouse) | 634 aa |
Protein Details: Q61510 (Trim25)
Protein Information
| Accession | Q61510 |
|---|---|
| Protein Names | E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147) |
| Gene Symbol | Trim25 |
| Organism | Mus musculus (Mouse) |
| Length | 634 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 34884899 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAELNPLAEE11LSCSVCLELF21KEPVTTPCGH31NFCMSCLDET41WVVQGPPYRC
51-10051PQCRKVYQVR61PQLQKNTVMC71AVVEQFLQAE81QARTPVDDWT91PPARFSASSA
101-150101ATQVACDHCL111TEIAVKTCLV121CMASFCQEHL131RPHFDSPAFQ141DHPLQSPIRD
151-200151LLRRKCTQHN161RLRELFCPEH171GECICHICLV181EHKTCSPTTL191SQASADLEYK
201-250201LRNKLTIMHS211HINGATKALE221DVRSKQQCVQ231DSMKRKMEQL241RQEYMEMKAV
251-300251IDAAETSSLR261KLKEEEKRVY271GKFDTIYQVL281VKKKSEMQKL291KAEVELIMDK
301-350301GDEFEFLEKA311AKLQGESTKP321VYIPKIDLDH331DLIMGIYQGA341ADLKSELKHS
351-400351IKKLQKKSEE361HNGSGNKGDQ371TQSTFKPVQP381SKKTIQEKKT391KKTPVAPGPP
401-450401SHFSPNKLPT411FGAPGQSLDS421KATSPDAAPK431ASAAQPDSVG441VKAKVLENFL
451-500451TKSRTELLEY461FVKVIFDYNT471AHNKVSLSNK481YTTASVSDGL491QHYRSHPQRF
501-550501TYCSQVLGLH511CYKNGIHYWE521VELQKNNFCG531VGICYGSMER541QGPESRLGRN
551-600551PNSWCVEWFN561NKISAWHNNV571EKTLPSTKAT581RVGVLLNCDH591GFVIFFAVTE
601-634601KVHLMYKFKV611DFTEALYPAF621WVFSAGTTLS631ICSK
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 13 | Zinc finger, RING-type, eukaryotic Zinc finger, RING-type RING/U-box Zinc finger, RING/FYVE/PHD-type RNF168/RNF169 E3 ubiquitin-protein ligase | - | - |
Deep-Palm: 0.81
|
|
| 16 | Zinc finger, RING-type, eukaryotic Zinc finger, RING-type RING/U-box Zinc finger, RING/FYVE/PHD-type RNF168/RNF169 E3 ubiquitin-protein ligase | - | - |
Deep-Palm: 0.79
|
|
| 28 | Zinc finger, RING-type, eukaryotic Zinc finger, RING-type RING/U-box Zinc finger, RING-type, conserved site Zinc finger, RING/FYVE/PHD-type E3 ubiquitin-protein ligase TRIM/RNF | - | - |
Deep-Palm: 0.15
|
|
| 33 | Zinc finger, RING-type, eukaryotic Zinc finger, RING-type RING/U-box Zinc finger, RING/FYVE/PHD-type E3 ubiquitin-protein ligase TRIM/RNF | - | - |
Deep-Palm: 0.05
|
|
| 36 | Zinc finger, RING-type, eukaryotic Zinc finger, RING-type RING/U-box Zinc finger, RING/FYVE/PHD-type E3 ubiquitin-protein ligase TRIM/RNF | - | - |
Deep-Palm: 0.03
|
|
| 50 | RING/U-box Zinc finger, RING/FYVE/PHD-type E3 ubiquitin-protein ligase TRIM/RNF | - | - |
Deep-Palm: 0.26
|
|
| 53 | - | - | - |
Deep-Palm: 0.13
|
|
| 70 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(34884899)
|
Deep-Palm: 0.82
|
| 106 | - | - | - |
Deep-Palm: 0.40
|
|
| 109 | - | - | - |
Deep-Palm: 0.23
|
|
| 118 | - | - | - |
Deep-Palm: 0.03
|
|
| 121 | - | - | - |
Deep-Palm: 0.03
|
|
| 126 | - | - | - |
Deep-Palm: 0.18
|
|
| 156 | - | - | - |
Deep-Palm: 0.72
|
|
| 167 | - | - | - |
Deep-Palm: 0.07
|
|
| 173 | - | - | - |
Deep-Palm: 0.07
|
|
| 175 | - | - | - |
Deep-Palm: 0.13
|
|
| 178 | - | - | - |
Deep-Palm: 0.12
|
|
| 185 | - |
MLE
(39008777)
| - |
Deep-Palm: 0.19
|
|
| 228 | - | - | - |
Deep-Palm: 0.93
|
|
| 503 | - | - | - |
Deep-Palm: 0.05
|
|
| 511 | - | - | - |
Deep-Palm: 0.04
|
|
| 529 | - | - | - |
Deep-Palm: 0.08
|
|
| 534 | - | - | - |
Deep-Palm: 0.77
|
|
| 555 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
Deep-Palm: 0.15
|
| 588 | - | - | - |
Deep-Palm: 0.59
|
|
| 632 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
5
Liver
Specificity: 1.000
5/5 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.