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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q61694 Hsd3b5 NADPH-dependent 3-keto-steroid reductase Hsd3b5 (3 … Mus musculus (Mouse) 373 aa

Protein Details: Q61694 (Hsd3b5)

Protein Information
AccessionQ61694
Protein NamesNADPH-dependent 3-keto-steroid reductase Hsd3b5 (3 beta-hydroxysteroid dehydrogenase type 5) (3 beta-hydroxysteroid dehydrogenase type V) (3 beta-HSD V) (EC 1.1.1.270) (Dihydrotestosterone 3-ketoreductase) (EC 1.1.1.210)
Gene SymbolHsd3b5
OrganismMus musculus (Mouse)
Length373 aa
IsoformsNo isoforms
Related PMIDs 28526873 34884899 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPGWSCLVTG11AGGFLGQRIV21RMLVQEEELQ31EIRALFRTFG41RKHEEELSKL
51-10051QTKAKVRVLK61GDILDAQCLK71RACQGMSAVI81HTAAAIDPLG91AASRQTILDV
101-150101NLKGTQLLLD111ACVEASVPTF121IYSSSVLVAG131PNSYKEIILN141AHEEEHREST
151-200151WPNPYPYSKR161MAEKAVLATN171GRLLKNGGTL181HTCALRLPFI191YGEECQVTST
201-250201TVKTALKNNS211IIKKNATFSI221ANPVYVGNAA231WAHILAARSL241QDPKKSPSIQ
251-300251GQFYYISDNT261PHQSYDDLNY271TLSKEWGLCL281DSGWSLPLSL291LYWLAFLLET
301-350301VSFLLRPVYN311YRPPFNRLLI321TVLNSVFTIS331YKKAQRDLGY341QPLVSWEEAK
351-373351QKTSEWIGTL361VKQHRETLHK371KSQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 NAD(P)-binding domain superfamily - -
Deep-Palm: 0.05
68 SWISSPALM DBPTM CYSMODDB 3-beta hydroxysteroid dehydrogenase/isomerase family
Liver (28526873)
-
GPS-Palm: 0.91
Deep-Palm: 0.95
73 SWISSPALM DBPTM CYSMODDB 3-beta hydroxysteroid dehydrogenase/isomerase family
Liver (28526873)
-
GPS-Palm: 0.91
Deep-Palm: 0.91
112 - - -
Deep-Palm: 0.93
183 SWISSPALM DBPTM CYSMODDB 3-beta hydroxysteroid dehydrogenase/isomerase family
liver (26165157)
-
GPS-Palm: 0.91
Deep-Palm: 0.96
195 SWISSPALM DBPTM CYSMODDB 3-beta hydroxysteroid dehydrogenase/isomerase family
Liver (28526873)
-
GPS-Palm: 0.89
Deep-Palm: 0.85
279 - - -
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
6
Liver
Specificity: 1.000
6/6 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine