Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q61753 Phgdh D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) … Mus musculus (Mouse) 533 aa

Protein Details: Q61753 (Phgdh)

Protein Information
AccessionQ61753
Protein NamesD-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (A10)
Gene SymbolPhgdh
OrganismMus musculus (Mouse)
Length533 aa
IsoformsNo isoforms
Related PMIDs 29217618 29660268 29733200 34200797 35358180 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAFANLRKVL11ISDSLDPCCR21KILQDGGLQV31VEKQNLSKEE41LIAELQDCEG
51-10051LIVRSATKVT61ADVINAAEKL71QVVGRAGTGV81DNVDLEAATR91KGILVMNTPN
101-150101GNSLSAAELT111CGMIMCLARQ121IPQATASMKD131GKWDRKKFMG141TELNGKTLGI
151-200151LGLGRIGREV161ATRMQSFGMK171TVGYDPIISP181EVAASFGVQQ191LPLEEIWPLC
201-250201DFITVHTPLL211PSTTGLLNDS221TFAQCKKGVR231VVNCARGGIV241DEGALLRALQ
251-300251SGQCAGAALD261VFTEEPPRDR271ALVDHENVIS281CPHLGASTKE291AQSRCGEEIA
301-350301VQFVDMVKGK311SLTGVVNAQA321LTSAFSPHTK331PWIGLAEAMG341TLMHAWAGSP
351-400351KGTIQVVTQG361TSLKNAGTCL371SPAVIVGLLR381EASKQADVNL391VNAKLLVKEA
401-450401GLNVTTSHNP411GVPGEQGSGE421CLLTVALAGA431PYQAVGLVQG441TTPMLQMLNG
451-500451AVFRPEVPLR461RGQPLLVFRA471QPSDPGMLPT481MIGLLAEAGV491QLLSYQTSMV
501-533501SDGEPWHVMG511LSSLLPSLET521WKQHVLEAFQ531FCF
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
18 -
Brain (34200797)
Brain (35358180)
GPS-Palm: 0.92
Deep-Palm: 0.98
19 -
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.98
48 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Formate/glycerate dehydrogenase catalytic domain-like - -
Deep-Palm: 0.97
111 - - -
Deep-Palm: 0.80
116 - - -
Deep-Palm: 0.92
200 - - -
Deep-Palm: 0.82
225 - - -
Deep-Palm: 0.95
234 - - -
Deep-Palm: 0.98
254 -
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.98
281 -
MLE (39008777)
Brain (35358180)
Deep-Palm: 0.96
295 - - -
Deep-Palm: 0.88
369 -
Brain (34200797)
Brain (35358180)
Deep-Palm: 0.98
421 - - -
Deep-Palm: 0.94
532 - - -
GPS-Palm: 0.98
Deep-Palm: 0.01
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Brain
Specificity: 0.167
5/5 (100.0%)
2
Testis
Specificity: 0.067
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.033
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
22
Brain tissue (Mass)
Specificity: 0.733
22/56 (39.3%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine