Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q62226 | Shh | Sonic hedgehog protein (SHH) (EC … | Mus musculus (Mouse) | 437 aa |
Protein Details: Q62226 (Shh)
Protein Information
| Accession | Q62226 |
|---|---|
| Protein Names | Sonic hedgehog protein (SHH) (EC 3.1.-.-) (HHG-1) (Shh unprocessed N-terminal signaling and C-terminal autoprocessing domains) (ShhNC) [Cleaved into: Sonic hedgehog protein N-product (ShhN) (Shh N-terminal processed signaling domains) (ShhNp) (Sonic hedgehog protein 19 kDa product)] |
| Gene Symbol | Shh |
| Organism | Mus musculus (Mouse) |
| Length | 437 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31311849 |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MLLLLARCFL11VILASSLLVC21PGLACGPGRG31FGKRRHPKKL41TPLAYKQFIP
51-10051NVAEKTLGAS61GRYEGKITRN71SERFKELTPN81YNPDIIFKDE91ENTGADRLMT
101-150101QRCKDKLNAL111AISVMNQWPG121VKLRVTEGWD131EDGHHSEESL141HYEGRAVDIT
151-200151TSDRDRSKYG161MLARLAVEAG171FDWVYYESKA181HIHCSVKAEN191SVAAKSGGCF
201-250201PGSATVHLEQ211GGTKLVKDLR221PGDRVLAADD231QGRLLYSDFL241TFLDRDEGAK
251-300251KVFYVIETLE261PRERLLLTAA271HLLFVAPHND281SGPTPGPSAL291FASRVRPGQR
301-350301VYVVAERGGD311RRLLPAAVHS321VTLREEEAGA331YAPLTAHGTI341LINRVLASCY
351-400351AVIEEHSWAH361RAFAPFRLAH371ALLAALAPAR381TDGGGGGSIP391AAQSATEARG
401-437401AEPTAGIHWY411SQLLYHIGTW421LLDSETMHPL431GMAVKSS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 8 | - | - | - |
Deep-Palm: 0.15
|
|
| 20 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.98
|
|
| 25 | DBPTM SWISSPALM | Hedgehog, N-terminal signalling domain | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.98
|
| 103 | - | - | - |
Deep-Palm: 0.83
|
|
| 184 | Hedgehog amino-terminal signalling domain |
Brain
(31311849)
| - |
Deep-Palm: 0.35
|
|
| 199 | - | - | - |
Deep-Palm: 0.94
|
|
| 349 | - | - | - |
Deep-Palm: 0.94
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Brain
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.