Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q63844 | Mapk3 | Mitogen-activated protein kinase 3 (MAP … | Mus musculus (Mouse) | 380 aa |
Protein Details: Q63844 (Mapk3)
Protein Information
| Accession | Q63844 |
|---|---|
| Protein Names | Mitogen-activated protein kinase 3 (MAP kinase 3) (MAPK 3) (EC 2.7.11.24) (ERT2) (Extracellular signal-regulated kinase 1) (ERK-1) (Insulin-stimulated MAP2 kinase) (MAP kinase isoform p44) (p44-MAPK) (MNK1) (Microtubule-associated protein 2 kinase) (p44-ERK1) |
| Gene Symbol | Mapk3 |
| Organism | Mus musculus (Mouse) |
| Length | 380 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31311849 34200797 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAAAAAPGG11GGGEPRGTAG21VVPVVPGEVE31VVKGQPFDVG41PRYTQLQYIG
51-10051EGAYGMVSSA61YDHVRKTRVA71IKKISPFEHQ81TYCQRTLREI91QILLRFRHEN
101-150101VIGIRDILRA111PTLEAMRDVY121IVQDLMETDL131YKLLKSQQLS141NDHICYFLYQ
151-200151ILRGLKYIHS161ANVLHRDLKP171SNLLINTTCD181LKICDFGLAR191IADPEHDHTG
201-250201FLTEYVATRW211YRAPEIMLNS221KGYTKSIDIW231SVGCILAEML241SNRPIFPGKH
251-300251YLDQLNHILG261ILGSPSQEDL271NCIINMKARN281YLQSLPSKTK291VAWAKLFPKS
301-350301DSKALDLLDR311MLTFNPNKRI321TVEEALAHPY331LEQYYDPTDE341PVAEEPFTFD
351-380351MELDDLPKER361LKELIFQETA371RFQPGAPEGP
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 83 | - |
Brain
(34200797)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.44
|
|
| 145 | - | - | - |
Deep-Palm: 0.37
|
|
| 179 | SWISSPALM DBPTM CYSMODDB | Protein kinase domain |
Brain
(31311849)
| - |
Deep-Palm: 0.91
|
| 184 | Protein kinase domain |
Brain
(34200797)
| - |
Deep-Palm: 0.56
|
|
| 234 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.30
|
|
| 272 | - | - | - |
Deep-Palm: 0.88
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Brain
Specificity: 0.160
4/4 (100.0%)
1
Testis
Specificity: 0.040
1/1 (100.0%)
1
Liver
Specificity: 0.040
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
19
Brain tissue (Mass)
Specificity: 0.760
19/56 (33.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.