Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q63HQ0-2 | AP1AR | AP-1 complex-associated regulatory protein (2c18) … | Homo sapiens (Human) | 269 aa |
Protein Details: Q63HQ0-2 (AP1AR)
Protein Information
| Accession | Q63HQ0-2 |
|---|---|
| Protein Names | AP-1 complex-associated regulatory protein (2c18) (Adaptor-related protein complex 1-associated regulatory protein) (Gamma-1-adaptin brefeldin A resistance protein) (GBAR) (Gamma-BAR) (Gamma-A1-adaptin and kinesin interactor) (Gadkin) |
| Gene Symbol | AP1AR |
| Organism | Homo sapiens (Human) |
| Length | 269 aa |
| Isoforms | |
| Related PMIDs | 31251020 32651440 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGNCCWTQCF11GLLRKEAGRL21QRVGGGGGSK31YFRTCSRGEH41LTIEFENLVE
51-10051SDEGESPGSS61HRPLTEEEIV71DLRERHYDSI81AEKQKDLDKK91IQKEQERQRI
101-150101VQQYHPSNNG111EYQSSGPEDD121FESCLRNMKS131QYEVFRSSRL141SSDATVLTPN
151-200151TESSCDLMTK161TKSTSGNDDS171TSLDLEWEDE181EGMNRMLPMR191ERSKTEEDIL
201-250201RAALKYSNKK211TGSNPTSASD221DSNGLEWEND231FVSAEMDDNG241NSEYSGFVNP
251-269251VLELSDSGIR261HSDTDQQTR
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 4 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 5 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.03
|
|
| 9 | - | - | - |
GPS-Palm: 0.92
Deep-Palm: 0.04
|
|
| 35 | AP-1 complex-associated regulatory protein | - | - |
Deep-Palm: 0.94
|
|
| 157 | - | - | - |
Deep-Palm: 0.57
|
|
| 188 | - | - | - |
Deep-Palm: 0.69
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
LNCaP
Specificity: 0.750
3/3 (100.0%)
1
Jurkat T cell
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 114 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 225 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 225 | R → C | 0.003774 | SNP | Missense Mutation | UCEC |