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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q68DH5 LMBRD2 G-protein coupled receptor-associated protein LMBRD2 … Homo sapiens (Human) 695 aa

Protein Details: Q68DH5 (LMBRD2)

Protein Information
Accession Q68DH5
Protein Names G-protein coupled receptor-associated protein LMBRD2 (LMBR1 domain-containing protein 2)
Gene Symbol LMBRD2
Organism Homo sapiens (Human)
Length 695 aa
Isoforms No isoforms
Related PMIDs 29575903 31251020 32944167 36430497
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.878
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
36
LNCaP cells
Specificity: 0.878
36/46 (78.3%)
4
PC3 cells
Specificity: 0.098
4/4 (100.0%)
1
Cerebral cortex
Specificity: 0.024
1/4 (25.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MSGAALGLEI11VFVFFLALFL21LHRYGDFKKQ31HRLVIIGTLL41AWYLCFLIVF
51-10051ILPLDVSTTI61YNRCKHAAAN71SSPPENSNIT81GLYATANPVP91SQHPCFKPWS
101-150101YIPDGIMPIF111WRVVYWTSQF121LTWILLPFMQ131SYARSGGFSI141TGKIKTALIE
151-200151NAIYYGTYLL161IFGAFLIYVA171VNPHLHLEWN181QLQTIGIAAA191NTWGLFLLVL
201-250201LLGYGLVEIP211RSYWNGAKRG221YLLMKTYFKA231AKLMTEKADA241EENLEDAMEE
251-300251VRKVNESIKY261NHPLRKCVDT271ILKKCPTEYQ281EKMGRNMDDY291EDFDEKHSIY
301-350301PSEKSLVKLH311KQVIYSVQRH321RRTQVQWQIL331LEQAFYLEDV341AKNETSATHQ
351-400351FVHTFQSPEP361ENRFIQYFYN371PTFEWYWECL381LRPWFYKILA391VVLSIFSVIV
401-450401VWSECTFFST411TPVLSLFAVF421IQLAEKTYNY431IYIEIACFLS441IFFLSICVYS
451-500451TVFRIRVFNY461YYLASHHQTD471AYSLLFSGML481FCRLTPPLCL491NFLGLTHMDS
501-550501SISHKNTQPT511AYTSIMGSMK521VLSFIADGFY531IYYPMLVVIL541CIATYFSLGT
551-600551RCLNLLGFQQ561FMGDDDMTSD571LVNEGKELIR581KEKRKRQRQE591EGENRRREWK
601-650601ERYGHNREDS611TRNRNIHTDP621KESNFSDVNT631NRSAFKYTRA641NNRTERDRIE
651-695651LLQDAEPLDF661NAETFTDDPL671ESESGRYQPG681GRYLSMSRSD691IFNDV
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
267 Prediction (Low) - -
275 Prediction (Low) - -
447 Prediction (High) - -
482 Prediction (Medium) - -
552 Experimental CYSMODDB SWISSPALM DBPTM - 29575903
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
14 F → C 0.001764 SNP Missense Mutation LUAD
45 C → C 0.004283 SNP Silent SKCM
46 F → C 0.001887 SNP Missense Mutation UCEC
213 Y → C 0.002033 SNP Missense Mutation LUSC
252 R → C 0.014599 SNP Missense Mutation READ
252 R → C 0.002141 SNP Missense Mutation SKCM
428 Y → C 0.002033 SNP Missense Mutation LUSC
456 R → C 0.004283 SNP Missense Mutation SKCM
477 S → C 0.002288 SNP Missense Mutation STAD
551 R → C 0.001969 SNP Missense Mutation HNSC