Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q68FF6 Git1 ARF GTPase-activating protein GIT1 (ARF … Mus musculus (Mouse) 770 aa

Protein Details: Q68FF6 (Git1)

Protein Information
AccessionQ68FF6
Protein NamesARF GTPase-activating protein GIT1 (ARF GAP GIT1) (G protein-coupled receptor kinase-interactor 1) (GRK-interacting protein 1)
Gene SymbolGit1
OrganismMus musculus (Mouse)
Length770 aa
IsoformsNo isoforms
Related PMIDs 31311849 34200797 35358180 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRKGPRAEV11CADCSAPDPG21WASISRGVLV31CDECCSVHRS41LGRHISIVKH
51-10051LRHSAWPPTL61LQMVHTLASN71GANSIWEHSL81LDPAQVQSGR91RKANPQDKVH
101-150101PIKSEFIRAK111YQMLAFVHKL121PCRDDDGVTA131KDLSKQLHSS141VRTGNLETCL
151-200151RLLSLGAQAN161FFHPEKGTTP171LHVAAKAGQT181LQAELLVVYG191ADPGSPDVNG
201-250201RTPIDYARQA211GHHELAERLV221ECQYELTDRL231AFYLCGRKPD241HKNGHYIIPQ
251-300251MADRSRQKCM261SQSLDLSELA271KAAKKKLQAL281SNRLFEELAM291DVYDEVDRRE
301-350301NDAVWLATQN311HSTLVTERSA321VPFLPVNPEY331SATRNQGRQK341LARFNAREFA
351-400351TLIIDILSEA361KRRQQGKSLS371SPTDNLELSA381RSQSELDDQH391DYDSVASDED
401-450401TDQEPLPSAG411ATRNNRARSM421DSSDLSDGAV431TLQEYLELKK441ALATSEAKVQ
451-500451QLMKVNSSLS461DELRRLQREI471HKLQAENLQL481RQPPGPVPPP491SLPSERAEHT
501-550501LMGPGGSTHR511RDRQAFSMYE521PGSALKPFGG531TPGDELATRL541QPFHSTELED
551-600551DAIYSVHVPA561GLYRIRKGVS571ASSVPFTPSS581PLLSCSQEGS591RHASKLSRHG
601-650601SGADSDYENT611QSGDPLLGLE621GKRFLELSKE631DELHPELESL641DGDLDPGLPS
651-700651TEDVILKTEQ661VTKNIQELLR671AAQEFKHDSF681VPCSEKIHLA691VTEMASLFPK
701-750701RPALEPVRSS711LRLLNASAYR721LQSECRKTVP731PEPGAPVDFQ741LLTQQVIQCA
751-770751YDIAKAAKQL761VTITTREKKQ
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
11 ArfGAP domain superfamily ARF GTPase-activating protein Git-like Arf GTPase activating protein ARFGAP/RecO-like zinc finger - -
Deep-Palm: 0.09
14 ArfGAP domain superfamily ARF GTPase-activating protein Git-like Arf GTPase activating protein ARFGAP/RecO-like zinc finger - -
Deep-Palm: 0.85
31 ArfGAP domain superfamily Arf GTPase activating protein ARF GTPase-activating protein Git-like ARFGAP/RecO-like zinc finger -
Brain (31311849)
Deep-Palm: 0.63
34 ArfGAP domain superfamily Arf GTPase activating protein ARF GTPase-activating protein Git-like ARFGAP/RecO-like zinc finger -
Brain (31311849)
Deep-Palm: 0.53
35 ArfGAP domain superfamily Arf GTPase activating protein ARF GTPase-activating protein Git-like ARFGAP/RecO-like zinc finger -
Brain (31311849)
Deep-Palm: 0.40
122 - - -
Deep-Palm: 0.82
149 - -
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.97
222 -
Brain (31311849)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.91
235 - -
Brain (31311849)
GPS-Palm: 0.91
Deep-Palm: 0.45
259 - - -
Deep-Palm: 0.92
585 -
brain (39008777)
Brain (35358180)
Deep-Palm: 0.96
683 G protein-coupled receptor kinase-interacting protein 1 C term
Brain (31311849)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.86
725 - - -
Deep-Palm: 0.94
749 - -
Brain (35358180)
Deep-Palm: 0.88
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
Brain
Specificity: 0.143
3/3 (100.0%)
1
Testis
Specificity: 0.048
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
17
Brain tissue (Mass)
Specificity: 0.810
17/56 (30.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine