Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6IAA8 | LAMTOR1; C11orf59; PDRO; PP7157 | Ragulator complex protein LAMTOR1 (Late … | Homo sapiens (Human) | 161 aa |
Protein Details: Q6IAA8 (LAMTOR1)
Protein Information
| Accession | Q6IAA8 |
|---|---|
| Protein Names | Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho) |
| Gene Symbol | LAMTOR1; C11orf59; PDRO; PP7157 |
| Organism | Homo sapiens (Human) |
| Length | 161 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 19801377 22496122 24357059 25914232 26111759 29575903 29733200 31251020 32651440 32944167 33636221 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.558
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
43
LNCaP cells
Specificity: 0.558
43/46 (93.5%)
13
Jurkat T cells
Specificity: 0.169
13/25 (52.0%)
4
PC3 cells
Specificity: 0.052
4/4 (100.0%)
4
HAP1 cells
Specificity: 0.052
4/10 (40.0%)
4
293T cells
Specificity: 0.052
4/10 (40.0%)
3
CEMx174 cells
Specificity: 0.039
3/3 (100.0%)
2
DU145 cells
Specificity: 0.026
2/2 (100.0%)
2
Endothelial cells
Specificity: 0.026
2/2 (100.0%)
1
HeLa cells
Specificity: 0.013
1/1 (100.0%)
1
Liver membrane
Specificity: 0.013
1/1 (100.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MGCCYSSENE11DSDQDREERK21LLLDPSSPPT31KALNGAEPNY41HSLPSARTDE
51-10051QALLSSILAK61TASNIIDVSA71ADSQGMEQHE81YMDRARQYST91RLAVLSSSLT
101-150101HWKKLPPLPS111LTSQPHQVLA121SEPIPFSDLQ131QVSRIAAYAY141SALSQIRVDA
151-161151KEELVVQFGI161P
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 3 | Prediction (High) | - | - |
| 4 | Prediction (High) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 91 | R → C | 0.002506 | SNP | Missense Mutation | COAD |