Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6IAA8 | LAMTOR1 | Ragulator complex protein LAMTOR1 (Late … | Homo sapiens (Human) | 161 aa |
Protein Details: Q6IAA8 (LAMTOR1)
Protein Information
| Accession | Q6IAA8 |
|---|---|
| Protein Names | Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho) |
| Gene Symbol | LAMTOR1 |
| Organism | Homo sapiens (Human) |
| Length | 161 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19137006 22496122 24357059 25914232 26111759 29575903 29733200 31251020 32651440 33636221 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGCCYSSENE11DSDQDREERK21LLLDPSSPPT31KALNGAEPNY41HSLPSARTDE
51-10051QALLSSILAK61TASNIIDVSA71ADSQGMEQHE81YMDRARQYST91RLAVLSSSLT
101-150101HWKKLPPLPS111LTSQPHQVLA121SEPIPFSDLQ131QVSRIAAYAY141SALSQIRVDA
151-161151KEELVVQFGI161P
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 3 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.02
|
|
| 4 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.364
8
Jurkat T cell
Specificity: 0.364
8/8 (100.0%)
4
LNCaP
Specificity: 0.182
4/4 (100.0%)
3
CEM 174 cell
Specificity: 0.136
3/3 (100.0%)
2
HeLa cell
Specificity: 0.091
2/2 (100.0%)
1
HAP1 cell
Specificity: 0.045
1/1 (100.0%)
1
EC cell
Specificity: 0.045
1/1 (100.0%)
1
293T cell
Specificity: 0.045
1/1 (100.0%)
1
heart
Specificity: 0.045
1/1 (100.0%)
1
HUVECs
Specificity: 0.045
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 91 | R → C | 0.002506 | SNP | Missense Mutation | COAD |