Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6ICB0 | DESI1; FAM152B; PPPDE2 | Desumoylating isopeptidase 1 (DeSI-1) (EC … | Homo sapiens (Human) | 168 aa |
Protein Details: Q6ICB0 (DESI1)
Protein Information
| Accession | Q6ICB0 |
|---|---|
| Protein Names | Desumoylating isopeptidase 1 (DeSI-1) (EC 3.4.-.-) (PPPDE peptidase domain-containing protein 2) (Palmitoyl protein thioesterase DESI1) (EC 3.1.2.22) (Polyubiquitinated substrate transporter) (POST) (S-depalmitoylase DESI1) |
| Gene Symbol | DESI1; FAM152B; PPPDE2 |
| Organism | Homo sapiens (Human) |
| Length | 168 aa |
| Isoforms | No isoforms |
| Related PMIDs | 37611173 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MEPPNLYPVK11LYVYDLSKGL21ARRLSPIMLG31KQLEGIWHTS41IVVHKDEFFF
51-10051GSGGISSCPP61GGTLLGPPDS71VVDVGSTEVT81EEIFLEYLSS91LGESLFRGEA
101-150101YNLFEHNCNT111FSNEVAQFLT121GRKIPSYITD131LPSEVLSTPF141GQALRPLLDS
151-168151IQIQPPGGSS161VGRPNGQS
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 58 | Prediction (Low) | - | - |
| 108 | Experimental | PPPDE putative peptidase domain | 37611173 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 98 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 108 | C → C | 0.003460 | SNP | Silent | CESC |