Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6PJ43 | ACTG1 | Actin | Homo sapiens (Human) | 263 aa |
Protein Details: Q6PJ43 (ACTG1)
Protein Information
| Accession | Q6PJ43 |
|---|---|
| Protein Names | Actin |
| Gene Symbol | ACTG1 |
| Organism | Homo sapiens (Human) |
| Length | 263 aa |
| Isoforms | No isoforms |
| Related PMIDs | 21076176 32944167 36430497 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501KANREKMTQI11MFETFNTPAM21YVAIQAVLSL31YASGRTTGIV41MDSGDGVTHT
51-10051VPIYEGYALP61HAILRLDLAG71RDLTDYLMKI81LTERGYSFTT91TAEREIVRDI
101-150101KEKLCYVALD111FEQEMATAAS121SSSLEKSYEL131PDGQVITIGN141ERFRCPEALF
151-200151QPSFLGMESC161GIHETTFNSI171MKCDVDIRKD181LYANTVLSGG191TTMYPGIADR
201-250201MQKEITALAP211STMKIKIIAP221PERKYSVWIG231GSILASLSTF241QQMWISKQEY
251-263251DESGPSIVHR261KCF
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 105 | - | - |
cerebral cortex
(36430497)
Unknown
(32651440)
|
GPS-Palm: 0.68
Deep-Palm: 0.94
|
|
| 145 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
Unknown
(32651440)
|
Deep-Palm: 0.69
|
|
| 160 | - | - |
cerebral cortex
(36430497)
LNCaP
(31251020)
Unknown
(32651440)
|
Deep-Palm: 0.14
|
|
| 173 | - | - |
Unknown
(32651440)
|
Deep-Palm: 0.19
|
|
| 262 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
PC3
Specificity: 0.400
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.100
1/1 (100.0%)
1
cerebral cortex
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Cerebral Cortex (Mass)
Specificity: 0.400
4/4 (100.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 95 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 218 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 257 | C → Y | 0.001969 | SNP | Missense Mutation | HNSC |
| 293 | L → Cfs*33 | 0.002033 | DEL | Frame Shift Del | THCA |
| 335 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 337 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |