Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q6PK56 EEF2 Elongation factor 2 Homo sapiens (Human) 583 aa

Protein Details: Q6PK56 (EEF2)

Protein Information
AccessionQ6PK56
Protein NamesElongation factor 2
Gene SymbolEEF2
OrganismHomo sapiens (Human)
Length583 aa
IsoformsNo isoforms
Related PMIDs 21076176 22496122 32944167 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MVNFTVDQIR11AIMDKKANIR21NMSVIAHVDH31GKSTLTDSLV41CKAGIIASAR
51-10051AGETRFTDTR61KDEQERCITI71KSTAISLFYE81LSENDLNFIK91QSKDGAGFLI
101-150101NLIDSPGHVD111FSSEVTAALR121VTDGALVVVD131CVSGVCVQTE141TVLRQAIAER
151-200151IKPVLMMNKM161DRALLELQLE171PEELYQTFQR181IVENVNVIIS191TYGEGESGPM
201-250201GNIMIDPVLG211TVGFGSGLHG221WAFTLKQFAE231MYVAKFAAKG241EGQLGPAERA
251-300251KKVEDMMKKL261WGDRYFDPAN271GKFSKSATSP281EGKKLPRTFC291QLILDPIFKV
301-350301FDAIMNFKKE311ETAKLIEKLD321IKLDSEDKDK331EGKPLLKAVM341RRWLPAGDAL
351-400351LQMITIHLPS361PVTAQKYRCE371LLYEGPPDDE381AAMGIKSCDP391KGPLMMYISK
401-450401MVPTSDKGRF411YAFGRVFSGL421VSTGLKVRIM431GPNYTPGKKE441DLYLKPIQRT
451-500451ILMMGRYVEP461IEDVPCGNIV471GLVGVDQFLV481KTGTITTFEH491AHNMRVMKFS
501-550501VSPVVRVAVE511AKNPADLPKL521VEGLKRLAKS531DPMVQCIIEE541SGEHIIAGAG
551-583551ELHLEICLKD561LEEDHACIPI571KKKKKKKKKK581KKK
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
41 Translational (tr)-type GTP-binding domain P-loop containing nucleoside triphosphate hydrolase TRANSLATION ELONGATION FACTOR-RELATED -
Unknown (32651440)
GPS-Palm: 0.89
Deep-Palm: 0.98
67 - - -
Deep-Palm: 0.75
131 - - -
Deep-Palm: 0.97
136 - - -
Deep-Palm: 0.95
290 - -
Unknown (32651440)
GPS-Palm: 0.89
Deep-Palm: 0.98
369 - -
LNCaP (31251020)
Unknown (32651440)
Deep-Palm: 0.79
388 - - -
GPS-Palm: 0.68
Deep-Palm: 0.72
466 - -
LNCaP (31251020)
Unknown (32651440)
Deep-Palm: 0.96
536 - - -
GPS-Palm: 0.68
Deep-Palm: 0.95
557 - - -
Deep-Palm: 0.94
567 - -
Unknown (32651440)
GPS-Palm: 0.91
Deep-Palm: 0.72
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.400
4
PC3
Specificity: 0.400
4/4 (100.0%)
4
cerebral cortex
Specificity: 0.400
4/4 (100.0%)
1
Jurkat T cell
Specificity: 0.100
1/1 (100.0%)
1
EC cell
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
20 R → C 0.001887 SNP Missense Mutation UCEC
162 R → C 0.001887 SNP Missense Mutation UCEC
287 R → C 0.001887 SNP Missense Mutation UCEC
397 Y → C 0.002427 SNP Missense Mutation BLCA
456 R → C 0.001887 SNP Missense Mutation UCEC
474 G → C 0.001887 SNP Missense Mutation UCEC
580 R → C 0.001014 SNP Missense Mutation BRCA
647 R → C 0.002288 SNP Missense Mutation STAD
701 R → C 0.002288 SNP Missense Mutation STAD
728 C → Wfs*23 0.002747 DEL Frame Shift Del LIHC
781 M → Cfs*20 0.001887 DEL Frame Shift Del UCEC