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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q6R5J7 EPB41L2 4.1G isoform (Erythrocyte membrane protein … Homo sapiens (Human) 383 aa

Protein Details: Q6R5J7 (EPB41L2)

Protein Information
AccessionQ6R5J7
Protein Names4.1G isoform (Erythrocyte membrane protein band 4.1 like 2)
Gene SymbolEPB41L2
OrganismHomo sapiens (Human)
Length383 aa
IsoformsNo isoforms
Related PMIDs 36430497
Database SourcesNo database sources
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MEEEETQLEE11ELDKAQEDIL21KHQASISELK31RNFMESTPEP41RPNEWEKRRI
51-10051TPLSLQTQGS61SHETLNIVEE71KKRAEVGKDE81RVITEEMNGK91EISPGSGPGE
101-150101IRKVEPVTQK111DSTSLSSESS121SSSSESEEED131VGEYRPHHRV141TEGTIREEQE
151-200151YEEEVEEEPR161PAAKVVEREE171AVPEASPVTQ181AGASVITVET191VIQENVGAQK
201-250201IPGEKSVHEG211ALKQDMGEEA221EEEPQKVNGE231VSHVDIDVLP241QIICCSEPPV
251-300251VKTEMVTISD261ASQRTEISTK271EVPIVQTETK281TITYESPQID291GGAGGDSGTL
301-350301LTAQTITSES311VSTTTTTHIT321KTVKGGISET331RIEKRIVITG341DGDIDHDQAL
351-383351AQAIREAREQ361HPDMSVTRVV371VHKETELAEE381GED
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
244 - - -
Deep-Palm: 0.42
245 - - -
Deep-Palm: 0.26
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
cerebral cortex
Specificity: 1.000
3/3 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
127 G → C 0.001887 SNP Missense Mutation UCEC
272 W → C 0.005435 SNP Missense Mutation ESCA
329 S → C 0.001969 SNP Missense Mutation HNSC
439 R → C 0.002506 SNP Missense Mutation COAD
439 R → C 0.004283 SNP Missense Mutation SKCM
452 R → C 0.001014 SNP Missense Mutation BRCA
488 C → F 0.001764 SNP Missense Mutation LUAD
516 R → C 0.001969 SNP Missense Mutation HNSC
516 R → C 0.002141 SNP Missense Mutation SKCM
541 R → C 0.001764 SNP Missense Mutation LUAD
653 R → C 0.001969 SNP Missense Mutation HNSC
653 R → C 0.017544 SNP Missense Mutation UCS
663 R → C 0.001014 SNP Missense Mutation BRCA
663 R → C 0.002288 SNP Missense Mutation STAD
773 Y → C 0.001887 SNP Missense Mutation UCEC
908 S → C 0.001014 SNP Missense Mutation BRCA