Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6ZMR3 | LDHAL6A | L-lactate dehydrogenase A-like 6A (LDHA-like … | Homo sapiens (Human) | 332 aa |
Protein Details: Q6ZMR3 (LDHAL6A)
Protein Information
| Accession | Q6ZMR3 |
|---|---|
| Protein Names | L-lactate dehydrogenase A-like 6A (LDHA-like protein 6A) (EC 1.1.1.27) |
| Gene Symbol | LDHAL6A |
| Organism | Homo sapiens (Human) |
| Length | 332 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MATIKSELIK11NFAEEEAIHH21NKISIVGTGS31VGVACAISIL41LKGLSDELVL
51-10051VDVDEGKLKG61ETMDLQHGSP71FMKMPNIVSS81KDYLVTANSN91LVIITAGARQ
101-150101KKGETRLDLV111QRNVSIFKLM121IPNITQYSPH131CKLLIVTNPV141DILTYVAWKL
151-200151SGFPKNRVIG161SGCNLDSARF171RYFIGQRLGI181HSESCHGLIL191GEHGDSSVPV
201-250201WSGVNIAGVP211LKDLNPDIGT221DKDPEQWENV231HKKVISSGYE241MVKMKGYTSW
251-300251GISLSVADLT261ESILKNLRRV271HPVSTLSKGL281YGINEDIFLS291VPCILGENGI
301-332301TDLIKVKLTL311EEEACLQKSA321ETLWEIQKEL331KL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 35 | L-lactate/malate dehydrogenase L-2-HYDROXYCARBOXYLATE DEHYDROGENASE (NAD(P)(+)) NAD(P)-binding domain superfamily Lactate/malate dehydrogenase, N-terminal | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.97
|
|
| 131 | - | - | - |
Deep-Palm: 0.81
|
|
| 163 | SWISSPALM DBPTM CYSMODDB | - | - |
Unknown
(32651440)
cerebral cortex
(36430497)
|
GPS-Palm: 0.95
Deep-Palm: 0.97
|
| 185 | - | - | - |
Deep-Palm: 0.84
|
|
| 293 | - | - | - |
Deep-Palm: 0.85
|
|
| 315 | - | - | - |
GPS-Palm: 0.89
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 99 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 106 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 148 | W → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 169 | R → C | 0.002020 | SNP | Missense Mutation | PRAD |
| 171 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 237 | S → delinsN*EC | 0.002033 | INS | Nonsense Mutation | THCA |
| 238 | G → C | 0.002747 | SNP | Missense Mutation | LIHC |