Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6ZUX7 | LHFPL2; KIAA0206 | LHFPL tetraspan subfamily member 2 … | Homo sapiens (Human) | 228 aa |
Protein Details: Q6ZUX7 (LHFPL2)
Protein Information
| Accession | Q6ZUX7 |
|---|---|
| Protein Names | LHFPL tetraspan subfamily member 2 protein (Lipoma HMGIC fusion partner-like 2 protein) |
| Gene Symbol | LHFPL2; KIAA0206 |
| Organism | Homo sapiens (Human) |
| Length | 228 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 29575903 31251020 32944167 37611173 |
| Database Sources | CysModDB dbPTM SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.600
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
6
LNCaP cells
Specificity: 0.600
6/46 (13.0%)
3
PC3 cells
Specificity: 0.300
3/4 (75.0%)
1
Endothelial cells
Specificity: 0.100
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MCHVIVTCRS11MLWTLLSIVV21AFAELIAFMS31ADWLIGKARS41RGGVEPAGPG
51-10051GGSPEPYHPT61LGIYARCIRN71PGVQHFQRDT81LCGPYAESFG91EIASGFWQAT
101-150101AIFLAVGIFI111LCMVALVSVF121TMCVQSIMKK131SIFNVCGLLQ141GIAGLFLILG
151-200151LILYPAGWGC161QKAIDYCGHY171ASAYKPGDCS181LGWAFYTAIG191GTVLTFICAV
201-228201FSAQAEIATS211SDKVQEEIEE221GKNLICLL
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 2 | Prediction (High) | - | - |
| 8 | Prediction (Medium) | - | - |
| 67 | Prediction (Low) | - | - |
| 123 | Prediction (Medium) | - | - |
| 136 | Prediction (Medium) | - | - |
| 160 | Prediction (Medium) | - | - |
| 167 | Prediction (Medium) | - | - |
| 198 | Prediction (Low) | - | - |
| 226 | Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) | - | 29575903, 37611173 |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 66 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 67 | C → C | 0.001887 | SNP | Silent | UCEC |
| 82 | C → C | 0.002141 | SNP | Silent | SKCM |
| 136 | C → C | 0.002747 | SNP | Silent | LIHC |
| 166 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |