Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q6ZUX7 | LHFPL2 | LHFPL tetraspan subfamily member 2 … | Homo sapiens (Human) | 228 aa |
Protein Details: Q6ZUX7 (LHFPL2)
Protein Information
| Accession | Q6ZUX7 |
|---|---|
| Protein Names | LHFPL tetraspan subfamily member 2 protein (Lipoma HMGIC fusion partner-like 2 protein) |
| Gene Symbol | LHFPL2 |
| Organism | Homo sapiens (Human) |
| Length | 228 aa |
| Isoforms | No isoforms |
| Related PMIDs | 24357059 32944167 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MCHVIVTCRS11MLWTLLSIVV21AFAELIAFMS31ADWLIGKARS41RGGVEPAGPG
51-10051GGSPEPYHPT61LGIYARCIRN71PGVQHFQRDT81LCGPYAESFG91EIASGFWQAT
101-150101AIFLAVGIFI111LCMVALVSVF121TMCVQSIMKK131SIFNVCGLLQ141GIAGLFLILG
151-200151LILYPAGWGC161QKAIDYCGHY171ASAYKPGDCS181LGWAFYTAIG191GTVLTFICAV
201-228201FSAQAEIATS211SDKVQEEIEE221GKNLICLL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 2 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.02
|
|
| 8 | - | - | - |
GPS-Palm: 0.88
Deep-Palm: 0.03
|
|
| 67 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.53
|
|
| 82 | - | - | - |
Deep-Palm: 0.64
|
|
| 112 | - | - | - |
Deep-Palm: 0.19
|
|
| 123 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.18
|
|
| 136 | - | - | - |
GPS-Palm: 0.82
Deep-Palm: 0.88
|
|
| 160 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.94
|
|
| 167 | - | - | - |
GPS-Palm: 0.84
Deep-Palm: 0.16
|
|
| 179 | - | - | - |
Deep-Palm: 0.10
|
|
| 198 | - | - | - |
GPS-Palm: 0.65
Deep-Palm: 0.61
|
|
| 226 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(37611173)
HeLa
(29575903)
| - |
GPS-Palm: 0.97
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.750
3
PC3
Specificity: 0.750
3/3 (100.0%)
1
HUVECs
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 66 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 67 | C → C | 0.001887 | SNP | Silent | UCEC |
| 82 | C → C | 0.002141 | SNP | Silent | SKCM |
| 136 | C → C | 0.002747 | SNP | Silent | LIHC |
| 166 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |