Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q6ZWX6 Eif2s1 Eukaryotic translation initiation factor 2 … Mus musculus (Mouse) 315 aa

Protein Details: Q6ZWX6 (Eif2s1)

Protein Information
AccessionQ6ZWX6
Protein NamesEukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)
Gene SymbolEif2s1
OrganismMus musculus (Mouse)
Length315 aa
IsoformsNo isoforms
Related PMIDs 29217618 29660268 29733200 34884899 35477839 37925639
Database SourcesSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MPGLSCRFYQ11HKFPEVEDVV21MVNVRSIAEM31GAYVSLLEYN41NIEGMILLSE
51-10051LSRRRIRSIN61KLIRIGRNEC71VVVIRVDKEK81GYIDLSKRRV91SPEEAIKCED
101-150101KFTKSKTVYS111ILRHVAEVLE121YTKDEQLESL131FQRTAWVFDD141KYKRPGYGAY
151-200151DAFKHAVSDP161SILDSLDLNE171DEREVLINNI181NRRLTPQAVK191IRADIEVACY
201-250201GYEGIDAVKE211ALRAGLNCST221ETMPIKINLI231APPRYVMTTT241TLERTEGLSV
251-300251LNQAMAVIKE261KIEEKRGVFN271VQMEPKVVTD281TDETELARQL291ERLERENAEV
301-315301DGDDDAEEME311AKAED
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
6 Nucleic acid-binding, OB-fold - -
GPS-Palm: 0.92
Deep-Palm: 0.02
70 - - -
GPS-Palm: 0.93
Deep-Palm: 0.96
98 - - -
Deep-Palm: 0.77
199 - - -
Deep-Palm: 0.96
218 - - -
GPS-Palm: 0.92
Deep-Palm: 0.93
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
5
Liver
Specificity: 0.500
5/5 (100.0%)
2
Brain
Specificity: 0.200
2/2 (100.0%)
2
Testis
Specificity: 0.200
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.100
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine