Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q71UA6 | SLC1A5 | Amino acid transporter | Homo sapiens (Human) | 541 aa |
Protein Details: Q71UA6 (SLC1A5)
Protein Information
| Accession | Q71UA6 |
|---|---|
| Protein Names | Amino acid transporter |
| Gene Symbol | SLC1A5 |
| Organism | Homo sapiens (Human) |
| Length | 541 aa |
| Isoforms | No isoforms |
| Related PMIDs | 19801377 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVADPPRDSK11GLAAAEPTAN21GGLALASIED31QGAAAGGYCG41SRDLVRRCLR
51-10051ANLLVLLTVV61AVVAGVALGL71GVSGAGGALA81LGPERLSAFV91FPGELLLRLL
101-150101RMIILPLVVC111SLIGGAASLD121PGALGRLGAW131ALLFFLVTTL141LASALGVGLA
151-200151LALQPGAASA161AINASVGAAG171SAENAPSKEV181LDSFLDLARN191IFPSNLVSAA
201-250201FRSYSTTYEE211RNITGTRVKV221PVGQEVEGMN231ILGLVVFAIV241FGVALRKLGP
251-300251EGELLIRFFN261SFNEATMVLV271SWIMWYAPVG281IMFLVAGKIV291EMEDVGLLFA
301-350301RLGKYILCCL311LGHAIHGLLV321LPLIYFLFTR331KNPYRFLWGI341VTPLATAFGT
351-400351SSSSATLPLM361MKCVEENNGV371AKHISRFILP381IGATVNMDGA391ALFQCVAAVF
401-450401IAQLSQQSLD411FVKIITILVT421ATASSVGAAG431IPAGGVLTLA441IILEAVNLPV
451-500451DHISLILAVD461WLVDRSCTVL471NVEGDALGAG481LLQNYVDRTE491SRSTEPELIQ
501-541501VKSELPLDPL511PVPTEEGNPL521LKHYRGPAGD531ATVASEKESV541M
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 39 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.98
|
|
| 48 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.98
|
|
| 110 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 308 | - | - | - |
GPS-Palm: 0.83
Deep-Palm: 0.96
|
|
| 309 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.98
|
|
| 363 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.70
|
|
| 395 | - | - | - |
Deep-Palm: 0.63
|
|
| 467 | - | - |
LNCaP
(31251020)
Unknown
(32651440)
|
GPS-Palm: 0.67
Deep-Palm: 0.92
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
DU145 cell
Specificity: 0.333
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
LNCaP cells (Mass)
Specificity: 0.667
2/4 (50.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 202 | R → C | 0.003460 | SNP | Missense Mutation | CESC |
| 305 | Y → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 330 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 395 | C → C | 0.004577 | SNP | Silent | STAD |
| 405 | S → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 467 | C → _V469delinsF | 0.002976 | DEL | In Frame Del | KIRC |