Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q76MZ3 | Ppp2r1a | Serine/threonine-protein phosphatase 2A 65 kDa … | Mus musculus (Mouse) | 589 aa |
Protein Details: Q76MZ3 (Ppp2r1a)
Protein Information
| Accession | Q76MZ3 |
|---|---|
| Protein Names | Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform (PP2Aa) (PP2A subunit A isoform PR65-alpha) (PP2A subunit A isoform R1-alpha) |
| Gene Symbol | Ppp2r1a |
| Organism | Mus musculus (Mouse) |
| Length | 589 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAADGDDSL11YPIAVLIDEL21RNEDVQLRLN31SIKKLSTIAL41ALGVERTRSE
51-10051LLPFLTDTIY61DEDEVLLALA71EQLGTFTTLV81GGPEYVHCLL91PPLESLATVE
101-150101ETVVRDKAVE111SLRAISHEHS121PSDLEAHFVP131LVKRLAGGDW141FTSRTSACGL
151-200151FSVCYPRVSS161AVKAELRQYF171RNLCSDDTPM181VRRAAASKLG191EFAKVLELDN
201-250201VKSEIIPMFS211NLASDEQDSV221RLLAVEACVN231IAQLLPQEDL241EALVMPTLRQ
251-300251AAEDKSWRVR261YMVADKFTEL271QKAVGPEITK281TDLVPAFQNL291MKDCEAEVRA
301-350301AASHKVKEFC311ENLSADCREN321VIMTQILPCI331KELVSDANQH341VKSALASVIM
351-400351GLSPILGKDN361TIEHLLPLFL371AQLKDECPEV381RLNIISNLDC391VNEVIGIRQL
401-450401SQSLLPAIVE411LAEDAKWRVR421LAIIEYMPLL431AGQLGVEFFD441EKLNSLCMAW
451-500451LVDHVYAIRE461AATSNLKKLV471EKFGKEWAHA481TIIPKVLAMS491GDPNYLHRMT
501-550501TLFCINVLSE511VCGQDITTKH521MLPTVLRMAG531DPVANVRFNV541AKSLQKIGPI
551-589551LDNSTLQSEV561KPILEKLTQD571QDVDVKYFAQ581EALTVLSLA
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 88 | - | - | - |
Deep-Palm: 0.98
|
|
| 148 | - |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 154 | - |
Brain
(34200797)
|
Brain
(35358180)
|
Deep-Palm: 0.90
|
|
| 174 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.97
|
|
| 228 | - | - | - |
Deep-Palm: 0.96
|
|
| 294 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.94
|
|
| 310 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.90
|
|
| 317 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.40
|
|
| 329 | SWISSPALM DBPTM CYSMODDB | PPP2R1A-like HEAT repeat |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.77
|
| 377 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.95
|
|
| 390 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.90
Deep-Palm: 0.87
|
| 447 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.77
|
|
| 504 | - | - | - |
Deep-Palm: 0.26
|
|
| 512 | - | - | - |
Deep-Palm: 0.37
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.462
6
Liver
Specificity: 0.150
6/6 (100.0%)
5
Brain
Specificity: 0.125
5/5 (100.0%)
2
Testis
Specificity: 0.050
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
27
Brain tissue (Mass)
Specificity: 0.675
27/56 (48.2%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.