Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q7L2M7 | PFKL | 6-phosphofructokinase type B (Phosphofructo-1-kinase isozyme … | Homo sapiens (Human) | 568 aa |
Protein Details: Q7L2M7 (PFKL)
Protein Information
| Accession | Q7L2M7 |
|---|---|
| Protein Names | 6-phosphofructokinase type B (Phosphofructo-1-kinase isozyme B) |
| Gene Symbol | PFKL |
| Organism | Homo sapiens (Human) |
| Length | 568 aa |
| Isoforms | No isoforms |
| Related PMIDs | 32944167 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.571
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
4
Cerebral cortex
Specificity: 0.571
4/4 (100.0%)
3
PC3 cells
Specificity: 0.429
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501GYLALVSALA11SGADWLFIPE21APPEDGWENF31MCERLGETRS41RGSRLNIIII
51-10051AEGAIDRNGK61PISSSYVKDL71VVQRLGFDTR81VTVLGHVQRG91GTPSAFDRIL
101-150101SSKMGMEAVM111ALLEATPDTP121ACVVTLSGNQ131SVRLPLMECV141QMTKEVQKAM
151-200151DDKRFDEATQ161LRGGSFENNW171NIYKLLAHQK181PPKEKSNFSL191AILNVGAPAA
201-250201GMNAAVRSAV211RTGISHGHTV221YVVHDGFEGL231AKGQVQEVGW241HDVAGWLGRG
251-300251GSMLGTKRTL261PKGQLESIVE271NIRIYGIHAL281LVVGGFEAYE291GVLQLVEARG
301-350301RYEELCIVMC311VIPATISNNV321PGTDFSLGSD331TAVNAAMESC341DRIKQSASGT
351-400351KRRVFIVETM361GGYCGYLATV371TGIAVGADAA381YVFEDPFNIH391DLKVNVEHMT
401-450401EKMKTDIQRG411LVLRNEKCHD421YYTTEFLYNL431YSSEGKGVFD441CRTNVLGHLQ
451-500451QGGAPTPFDR461NYGTKLGVKA471MLWLSEKLRE481VYRKGRVFAN491APDSACVIGL
501-550501KKKAVAFSPV511TELKKDTDFE521HRMPREQWWL531SLRLMLKMLA541QYRISMAAYV
551-568551SGELEHVTRR561TLSMDKGF
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 32 | Prediction (Medium) | - | - |
| 139 | Prediction (Medium) | - | - |
| 310 | Prediction (Low) | - | - |
| 340 | Prediction (Medium) | - | - |
| 418 | Prediction (Low) | - | - |
| 496 | Prediction (Medium) | - | - |
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 89 | C → W | 0.001764 | SNP | Missense Mutation | LUAD |
| 98 | R → C | 0.002545 | SNP | Missense Mutation | GBM |
| 164 | S → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 184 | R → C | 0.005618 | SNP | Missense Mutation | PAAD |
| 513 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 630 | C → C | 0.001887 | SNP | Silent | UCEC |
| 653 | C → F | 0.002033 | SNP | Missense Mutation | LUSC |
| 734 | R → C | 0.002506 | SNP | Missense Mutation | COAD |