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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q7L5N7 LPCAT2 Lysophosphatidylcholine acyltransferase 2 (LPC acyltransferase … Homo sapiens (Human) 544 aa

Protein Details: Q7L5N7 (LPCAT2)

Protein Information
AccessionQ7L5N7
Protein NamesLysophosphatidylcholine acyltransferase 2 (LPC acyltransferase 2) (LPCAT-2) (LysoPC acyltransferase 2) (EC 2.3.1.23) (1-acylglycerol-3-phosphate O-acyltransferase 11) (1-AGP acyltransferase 11) (1-AGPAT 11) (EC 2.3.1.51) (1-acylglycerophosphocholine O-acyltransferase) (1-alkenylglycerophosphocholine O-acyltransferase) (EC 2.3.1.25) (1-alkylglycerophosphocholine O-acetyltransferase) (EC 2.3.1.67) (Acetyl-CoA:lyso-platelet-activating factor acetyltransferase) (Acetyl-CoA:lyso-PAF acetyltransferase) (Lyso-PAF acetyltransferase) (LysoPAFAT) (Acyltransferase-like 1) (Lysophosphatidic acid acyltransferase alpha) (LPAAT-alpha)
Gene SymbolLPCAT2
OrganismHomo sapiens (Human)
Length544 aa
IsoformsNo isoforms
Related PMIDs No related PMIDs
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MSRCAQAAEV11AATVPGAGVG21NVGLRPPMVP31RQASFFPPPV41PNPFVQQTQI
51-10051GSARRVQIVL61LGIILLPIRV71LLVALILLLA81WPFAAISTVC91CPEKLTHPIT
101-150101GWRRKITQTA111LKFLGRAMFF121SMGFIVAVKG131KIASPLEAPV141FVAAPHSTFF
151-200151DGIACVVAGL161PSMVSRNENA171QVPLIGRLLR181AVQPVLVSRV191DPDSRKNTIN
201-250201EIIKRTTSGG211EWPQILVFPE221GTCTNRSCLI231TFKPGAFIPG241VPVQPVLLRY
251-300251PNKLDTVTWT261WQGYTFIQLC271MLTFCQLFTK281VEVEFMPVQV291PNDEEKNDPV
301-350301LFANKVRNLM311AEALGIPVTD321HTYEDCRLMI331SAGQLTLPME341AGLVEFTKIS
351-400351RKLKLDWDGV361RKHLDEYASI371ASSSKGGRIG381IEEFAKYLKL391PVSDVLRQLF
401-450401ALFDRNHDGS411IDFREYVIGL421AVLCNPSNTE431EIIQVAFKLF441DVDEDGYITE
451-500451EEFSTILQAS461LGVPDLDVSG471LFKEIAQGDS481ISYEEFKSFA491LKHPEYAKIF
501-544501TTYLDLQTCH511VFSLPKEVQT521TPSTASNKVS531PEKHEESTSD541KKDD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
4 - - -
GPS-Palm: 0.92
Deep-Palm: 0.04
90 - - -
Deep-Palm: 0.96
91 - - -
GPS-Palm: 0.73
Deep-Palm: 0.93
155 - - -
Deep-Palm: 0.84
223 - - -
Deep-Palm: 0.92
228 SWISSPALM DBPTM CYSMODDB Acyltransferase - -
Deep-Palm: 0.94
270 - - -
Deep-Palm: 0.06
275 - - -
GPS-Palm: 0.72
Deep-Palm: 0.06
326 - - -
Deep-Palm: 0.88
424 - - -
GPS-Palm: 0.83
Deep-Palm: 0.92
509 - - -
GPS-Palm: 0.73
Deep-Palm: 0.75
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
69 R → C 0.002141 SNP Missense Mutation SKCM
101 G → C 0.004219 SNP Missense Mutation SARC
113 F → C 0.002545 SNP Missense Mutation GBM
189 R → C 0.001969 SNP Missense Mutation HNSC
223 C → C 0.001887 SNP Silent UCEC
226 R → C 0.002141 SNP Missense Mutation SKCM
326 C → C 0.002288 SNP Silent STAD
483 Y → C 0.001764 SNP Missense Mutation LUAD
488 S → C 0.002545 SNP Missense Mutation GBM