Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q7TME0 Plppr4 Phospholipid phosphatase-related protein type 4 … Mus musculus (Mouse) 766 aa

Protein Details: Q7TME0 (Plppr4)

Protein Information
AccessionQ7TME0
Protein NamesPhospholipid phosphatase-related protein type 4 (Brain-specific phosphatidic acid phosphatase-like protein 1) (Inactive 2-lysophosphatidate phosphatase PLPPR4) (Lipid phosphate phosphatase-related protein type 4) (Plasticity-related gene 1 protein) (PRG-1)
Gene SymbolPlppr4
OrganismMus musculus (Mouse)
Length766 aa
IsoformsNo isoforms
Related PMIDs 29733200 34200797 35358180 35477839 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MQRAGSSGAR11GECDISGAGR21LRLEQAARLG31GRTVHTSPGG41GLGARQAAGM
51-10051SAKERPKGKV61IKDSVTLLPC71FYFVELPILA81SSVVSLYFLE91LTDVFKPVHS
101-150101GFSCYDRSLS111MPYIEPTQEA121IPFLMLLSLA131FAGPAITIMV141GEGILYCCLS
151-200151KRRNGAGLEP161NINAGGCNFN171SFLRRAVRFV181GVHVFGLCST191ALITDIIQLS
201-250201TGYQAPYFLT211VCKPNYTSLN221VSCKENSYIV231EDICSGSDLT241VINSGRKSFP
251-300251SQHATLAAFA261AVYVSMYFNS271TLTDSSKLLK281PLLVFTFIIC291GIICGLTRIT
301-350301QYKNHPVDVY311CGFLIGGGIA321LYLGLYAVGN331FLPSEDSMLQ341HRDALRSLTD
351-400351LNQDPSRVLS361AKNGSSGDGI371AHTEGILNRN381HRDASSLTNL391KRANADVEII
401-450401TPRSPMGKES411MVTFSNTLPR421ANTPSVEDPV431RRNASIHASM441DSARSKQLLT
451-500451QWKSKNESRK461MSLQVMDTEP471EGQSPPRSIE481MRSSSEPSRV491GVNGDHHVPG
501-550501NQYLKIQPGT511VPGCNNSMPG521GPRVSIQSRP531GSSQLVHIPE541ETQENISTSP
551-600551KSSSARAKWL561KAAEKTVACN571RSNNQPRIMQ581VIAMSKQQGV591LQSSPKNAEG
601-650601STVTCTGSIR611YKTLTDHEPS621GIVRVEAHPE631NNRPIIQIPS641STEGEGSGSW
651-700651KWKAPEKSSL661RQTYELNDLN671RDSESCESLK681DSFGSGDRKR691SNIDSNEHHH
701-750701HGITTIRVTP711VEGSEIGSET721LSVSSSRDST731LRRKGNIILI741PERSNSPENT
751-766751RNIFYKGTSP761TRAYKD
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
13 - -
Brain (35358180)
GPS-Palm: 0.90
Deep-Palm: 0.68
70 - - -
Deep-Palm: 0.96
104 - - -
Deep-Palm: 0.65
147 - - -
GPS-Palm: 0.95
Deep-Palm: 0.95
148 - - -
GPS-Palm: 0.96
Deep-Palm: 0.92
167 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
-
Deep-Palm: 0.93
188 - - -
Deep-Palm: 0.86
212 - - -
Deep-Palm: 0.42
223 - - -
Deep-Palm: 0.11
234 - -
Brain (35358180)
Deep-Palm: 0.55
290 - - -
GPS-Palm: 0.91
Deep-Palm: 0.92
294 - - -
GPS-Palm: 0.93
Deep-Palm: 0.33
311 - - -
Deep-Palm: 0.27
514 - -
Brain (35358180)
Deep-Palm: 0.57
569 - - -
Deep-Palm: 0.93
605 -
Brain (34200797)
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.78
676 - -
Brain (35358180)
Deep-Palm: 0.83
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
4
Brain
Specificity: 0.143
4/4 (100.0%)
2
Testis
Specificity: 0.071
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
22
Brain tissue (Mass)
Specificity: 0.786
22/56 (39.3%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine