Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q7TMM9 Tubb2a Tubulin beta-2A chain Mus musculus (Mouse) 445 aa

Protein Details: Q7TMM9 (Tubb2a)

Protein Information
AccessionQ7TMM9
Protein NamesTubulin beta-2A chain
Gene SymbolTubb2a
OrganismMus musculus (Mouse)
Length445 aa
IsoformsNo isoforms
Related PMIDs 28526873 29733200 31311849 34200797 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MREIVHIQAG11QCGNQIGAKF21WEVISDEHGI31DPTGSYHGDS41DLQLERINVY
51-10051YNEAAGNKYV61PRAILVDLEP71GTMDSVRSGP81FGQIFRPDNF91VFGQSGAGNN
101-150101WAKGHYTEGA111ELVDSVLDVV121RKESESCDCL131QGFQLTHSLG141GGTGSGMGTL
151-200151LISKIREEYP161DRIMNTFSVM171PSPKVSDTVV181EPYNATLSVH191QLVENTDETY
201-250201SIDNEALYDI211CFRTLKLTTP221TYGDLNHLVS231ATMSGVTTCL241RFPGQLNADL
251-300251RKLAVNMVPF261PRLHFFMPGF271APLTSRGSQQ281YRALTVPELT291QQMFDSKNMM
301-350301AACDPRHGRY311LTVAAIFRGR321MSMKEVDEQM331LNVQNKNSSY341FVEWIPNNVK
351-400351TAVCDIPPRG361LKMSATFIGN371STAIQELFKR381ISEQFTAMFR391RKAFLHWYTG
401-445401EGMDEMEFTE411AESNMNDLVS421EYQQYQDATA431DEQGEFEEEE441GEDEA
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
12 SWISSPALM DBPTM CYSMODDB OS01G0282866 PROTEIN Tubulin/FtsZ, GTPase domain superfamily Tubulin/FtsZ family GTPase domain
Liver (28526873)
Brain (31311849)
-
Deep-Palm: 0.03
127 Tubulin/FtsZ family GTPase domain
Brain (34200797)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.82
129 Tubulin/FtsZ family GTPase domain
Brain (34200797)
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.88
211 - -
Brain (35358180)
Deep-Palm: 0.39
239 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
Brain (31311849)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.90
Deep-Palm: 0.97
303 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.57
354 SWISSPALM DBPTM CYSMODDB Tubulin C-terminal domain
Brain (31311849)
MLE (39008777)
Liver (28526873)
Brain (35358180)
Brain (31311849)
GPS-Palm: 0.92
Deep-Palm: 0.68
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.455
5
Brain
Specificity: 0.119
5/5 (100.0%)
4
Liver
Specificity: 0.095
4/4 (100.0%)
2
Testis
Specificity: 0.048
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
31
Brain tissue (Mass)
Specificity: 0.738
31/56 (55.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine