Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q7TPR4 Actn1 Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin … Mus musculus (Mouse) 892 aa

Protein Details: Q7TPR4 (Actn1)

Protein Information
Accession Q7TPR4
Protein Names Alpha-actinin-1 (Alpha-actinin cytoskeletal isoform) (F-actin cross-linking protein) (Non-muscle alpha-actinin-1)
Gene Symbol Actn1
Organism Mus musculus (Mouse)
Length 892 aa
Isoforms No isoforms
Related PMIDs 26165157 28526873 29733200 31311849 34200797 34884899 35477839 37925639
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.613
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.613
19/19 (100.0%)
8
Brain tissue
Specificity: 0.258
8/12 (66.7%)
3
Liver membrane
Specificity: 0.097
3/6 (50.0%)
1
Testis
Specificity: 0.032
1/2 (50.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Neural Stem Cells
Specificity: 0.000
0/3 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MDHYDSQQTN11DYMQPEEDWD21RDLLLDPAWE31KQQRKTFTAW41CNSHLRKAGT
51-10051QIENIEEDFR61DGLKLMLLLE71VISGERLAKP81ERGKMRVHKI91SNVNKALDFI
101-150101ASKGVKLVSI111GAEEIVDGNV121KMTLGMIWTI131ILRFAIQDIS141VEETSAKEGL
151-200151LLWCQRKTAP161YKNVNIQNFH171ISWKDGLGFC181ALIHRHRPEL191IDYGKLRKDD
201-250201PLTNLNTAFD211VAERFLDIPK221MLDAEDIVGT231ARPDEKAIMT241YVSSFYHAFS
251-300251GAQKAETAAN261RICKVLAVNQ271ENEQLMEDYE281KLASDLLEWI291RRTIPWLENR
301-350301VPENTMHAMQ311QKLEDFRDYR321RLHKPPKVQE331KCQLEINFNT341LQTKLRLSNR
351-400351PAFMPSEGRM361VSDINNAWGC371LEQAEKGYEE381WLLNEIRRLE391RLDHLAEKFR
401-450401QKASIHEAWT411DGKEAMLRQK421DYETATLSEI431KALLKKHEAF441ESDLAAHQDR
451-500451VEQIAAIAQE461LNELDYYDSP471SVNARCQKIC481DQWDNLGALT491QKRREALERT
501-550501EKLLETIDQL511YLEYAKRAAP521FNNWMEGAME531DLQDTFIVHT541IEEIQGLTTA
551-600551HEQFKATLPD561ADKERLAILG571IHNEVSKIVQ581TYHVNMAGTN591PYTTITPQEI
601-650601NGKWDHVRQL611VPRRDQALTE621EHARQQHNER631LRKQFGAQAN641VIGPWIQTKM
651-700651EEIGRISIEM661HGTLEDQLSH671LRQYEKSIVN681YKPKIDQLEC691DHQLIQEALI
701-750701FDNKHTNYNM711EHIRVGWEQL721LTTIARTINE731VENQILTRDA741KGISQEQMNE
751-800751FRASFNHFDR761DHSGTLGPEE771FKACLISLGY781DIGNDPQGEA791EFARIMSIVD
801-850801PNRLGVVTFQ811AFIDFMSRET821ADTDTADQVM831ASFKILAGDK841NYITEDELRR
851-892851ELPPDQAEYC861IARMAPYAGP871DSVPGALDYM881SFSTALYGES891DL
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
41 Experimental Calponin homology (CH) domain 31311849
154 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Calponin homology (CH) domain 28526873
180 Experimental CYSMODDB SWISSPALM DBPTM Prediction (High) Calponin homology (CH) domain 26165157, 31311849
332 Experimental - 31311849
480 Experimental Spectrin repeat 31311849
690 Experimental - 31311849
860 Experimental Ca2+ insensitive EF hand 34200797
Conservation Scores
PhyloP
PhastCons