Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q7Z5G3 | ACSS1 | Acetyl-coenzyme A synthetase (EC 6.2.1.1) | Homo sapiens (Human) | 687 aa |
Protein Details: Q7Z5G3 (ACSS1)
Protein Information
| Accession | Q7Z5G3 |
|---|---|
| Protein Names | Acetyl-coenzyme A synthetase (EC 6.2.1.1) |
| Gene Symbol | ACSS1 |
| Organism | Homo sapiens (Human) |
| Length | 687 aa |
| Isoforms | No isoforms |
| Related PMIDs | 36430497 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count
Color Intensity: Positive Ratio
3
Cerebral cortex
Specificity: 1.000
3/4 (75.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Endothelial cells
Specificity: 0.000
0/2 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MAARTLGRGV11GRLLGSLRGL21SGQPARPPCG31VSAPRRAASG41PSGSAPAVAA
51-10051AAAQPGSYPA61LSAQAAREPA71AFWGPLARDT81LVWDTPYHTV91WDCDFSTGKI
101-150101GWFLGGQLNV111SVNCLDQHVR121KSPESVALIW131ERDEPGTEVR141ITYRELLETT
151-200151CRLANTLKRH161GVHRGDRVAI171YMPVSPLAVA181AMLACARIGA191VHTVIFAGFS
201-250201AESLAGRIND211AKCKVVITFN221QGLRGGRVVE231LKKIVDEAVK241HCPTVQHVLV
251-300251AHRTDNKVHM261GDLDVPLEQE271MAKEDPVCAP281ESMGSEDMLF291MLYTSGSTGM
301-350301PKGIVHTQAG311YLLYAALTHK321LVFDHQPGDI331FGCVADIGWI341TGHSYVVYGP
351-400351LCNGATSVLF361ESTPVYPNAG371RYWETVERLK381INQFYGAPTA391VRLLLKYGDA
401-450401WVKKYDRSSL411RTLGSVGEPI421NCEAWEWLHR431VVGDSRCTLV441DTWWQTGGIC
451-500451IAPRPSEEGA461EILPAMAMRP471FFGIVPVLMD481EKGSVMEGSN491VSGALCISQA
501-550501WPGMARTIYG511DHQRFVDAYF521KAYPGYYFTG531DGAYRTEGGY541YQITGRMDDV
551-600551INISGHRLGT561AEIEDAIADH571PAVPESAVIG581YPHDIKGEAA591FAFIVVKDSA
601-650601GDSDVVVQEL611KSMVATKIAK621YAVPDEILVV631KRLPKTRSGK641VMRRLLRKII
651-687651TSEAQELGDT661TTLEDPSIIA671EILSVYQKCK681DKQAAAK
Palmitoylation Sites Details
| Position | Sources | Domains | Experimental PMIDs |
|---|---|---|---|
| 29 | Prediction (Medium) | - | - |
| 151 | Prediction (High) | - | - |
| 185 | Prediction (Medium) | - | - |
| 213 | Prediction (Medium) | - | - |
| 450 | Prediction (Medium) | - | - |
| 679 | Prediction (Low) | - | - |
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 164 | R → C | 0.002288 | SNP | Missense Mutation | STAD |
| 213 | C → R | 0.001887 | SNP | Missense Mutation | UCEC |
| 373 | W → C | 0.002545 | SNP | Missense Mutation | GBM |
| 407 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 409 | S → C | 0.003460 | SNP | Missense Mutation | CESC |
| 422 | C → Y | 0.003460 | SNP | Missense Mutation | CESC |
| 437 | C → S | 0.002294 | SNP | Missense Mutation | OV |