Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q7Z5R6 | APBB1IP | Amyloid beta A4 precursor protein-binding … | Homo sapiens (Human) | 666 aa |
Protein Details: Q7Z5R6 (APBB1IP)
Protein Information
| Accession | Q7Z5R6 |
|---|---|
| Protein Names | Amyloid beta A4 precursor protein-binding family B member 1-interacting protein (APBB1-interacting protein 1) (Proline-rich EVH1 ligand 1) (PREL-1) (Proline-rich protein 73) (Rap1-GTP-interacting adapter molecule) (RIAM) (Retinoic acid-responsive proline-rich protein 1) (RARP-1) |
| Gene Symbol | APBB1IP |
| Organism | Homo sapiens (Human) |
| Length | 666 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31382980 |
| Database Sources | No database sources |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGESSEDIDQ11MFSTLLGEMD21LLTQSLGVDT31LPPPDPNPPR41AEFNYSVGFK
51-10051DLNESLNALE61DQDLDALMAD71LVADISEAEQ81RTIQAQKESL91QNQHHSASLQ
101-150101ASIFSGAASL111GYGTNVAATG121ISQYEDDLPP131PPADPVLDLP141LPPPPPEPLS
151-200151QEEEEAQAKA161DKIKLALEKL171KEAKVKKLVV181KVHMNDNSTK191SLMVDERQLA
201-250201RDVLDNLFEK211THCDCNVDWC221LYEIYPELQI231ERFFEDHENV241VEVLSDWTRD
251-300251TENKILFLEK261EEKYAVFKNP271QNFYLDNRGK281KESKETNEKM291NAKNKESLLE
301-350301ESFCGTSIIV311PELEGALYLK321EDGKKSWKRR331YFLLRASGIY341YVPKGKTKTS
351-400351RDLACFIQFE361NVNIYYGTQH371KMKYKAPTDY381CFVLKHPQIQ391KESQYIKYLC
401-450401CDDTRTLNQW411VMGIRIAKYG421KTLYDNYQRA431VAKAGLASRW441TNLGTVNAAA
451-500451PAQPSTGPKT461GTTQPNGQIP471QATHSVSAVL481QEAQRHAETS491KDKKPALGNH
501-550501HDPAVPRAPH511APKSSLPPPP521PVRRSSDTSG531SPATPLKAKG541TGGGGLPAPP
551-600551DDFLPPPPPP561PPLDDPELPP571PPPDFMEPPP581DFVPPPPPSY591AGIAGSELPP
601-650601PPPPPPAPAP611APVPDSARPP621PAVAKRPPVP631PKRQENPGHP641GGAGGGEQDF
651-666651MSDLMKALQK661KRGNVS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 213 | - | - | - |
Deep-Palm: 0.04
|
|
| 215 | - | - | - |
Deep-Palm: 0.06
|
|
| 220 | - | - | - |
Deep-Palm: 0.03
|
|
| 304 | - | - | - |
GPS-Palm: 0.76
Deep-Palm: 0.96
|
|
| 355 | - | - | - |
GPS-Palm: 0.78
Deep-Palm: 0.21
|
|
| 381 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.45
|
|
| 400 | - | - | - |
GPS-Palm: 0.72
Deep-Palm: 0.12
|
|
| 401 | - | - | - |
GPS-Palm: 0.71
Deep-Palm: 0.10
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
U937 cell
Specificity: 1.000
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 105 | S → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 213 | C → C | 0.002288 | SNP | Silent | STAD |
| 213 | C → C | 0.002545 | SNP | Silent | GBM |
| 330 | R → C | 0.002506 | SNP | Missense Mutation | COAD |
| 381 | C → R | 0.002141 | SNP | Missense Mutation | SKCM |
| 410 | W → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 440 | W → C | 0.001764 | SNP | Missense Mutation | LUAD |