Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q7Z6A9 | BTLA | B- and T-lymphocyte attenuator (B- … | Homo sapiens (Human) | 289 aa |
Protein Details: Q7Z6A9 (BTLA)
Protein Information
| Accession | Q7Z6A9 |
|---|---|
| Protein Names | B- and T-lymphocyte attenuator (B- and T-lymphocyte-associated protein) (CD antigen CD272) |
| Gene Symbol | BTLA |
| Organism | Homo sapiens (Human) |
| Length | 289 aa |
| Isoforms | No isoforms |
| Related PMIDs | 25914232 |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MKTLPAMLGT11GKLFWVFFLI21PYLDIWNIHG31KESCDVQLYI41KRQSEHSILA
51-10051GDPFELECPV61KYCANRPHVT71WCKLNGTTCV81KLEDRQTSWK91EEKNISFFIL
101-150101HFEPVLPNDN111GSYRCSANFQ121SNLIESHSTT131LYVTDVKSAS141ERPSKDEMAS
151-200151RPWLLYRLLP161LGGLPLLITT171CFCLFCCLRR181HQGKQNELSD191TAGREINLVD
201-250201AHLKSEQTEA211STRQNSQVLL221SETGIYDNDP231DLCFRMQEGS241EVYSNPCLEE
251-289251NKPGIVYASL261NHSVIGPNSR271LARNVKEAPT281EYASICVRS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 34 | B- and T-lymphocyte attenuator | - | - |
Deep-Palm: 0.45
|
|
| 58 | - | - | - |
Deep-Palm: 0.17
|
|
| 63 | - | - | - |
Deep-Palm: 0.25
|
|
| 72 | - | - | - |
Deep-Palm: 0.13
|
|
| 79 | - | - | - |
GPS-Palm: 0.86
Deep-Palm: 0.42
|
|
| 115 | - | - | - |
Deep-Palm: 0.06
|
|
| 171 | - | - | - |
GPS-Palm: 0.95
Deep-Palm: 0.98
|
|
| 173 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.98
|
|
| 176 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.97
|
|
| 177 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.97
|
|
| 233 | - | - | - |
Deep-Palm: 0.42
|
|
| 247 | - | - | - |
Deep-Palm: 0.80
|
|
| 286 | - | - | - |
GPS-Palm: 0.97
Deep-Palm: 0.04
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
CEM 174 cell
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 58 | C → C | 0.001887 | SNP | Silent | UCEC |
| 63 | C → R | 0.002020 | SNP | Missense Mutation | PRAD |
| 71 | W → C | 0.002747 | SNP | Missense Mutation | LIHC |
| 171* | C → ? | 0.002288 | DEL | Frame Shift Del | STAD |