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Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q86T13 CLEC14A; C14orf27; EGFR5; UNQ236/PRO269 C-type lectin domain family 14 … Homo sapiens (Human) 490 aa

Protein Details: Q86T13 (CLEC14A)

Protein Information
Accession Q86T13
Protein Names C-type lectin domain family 14 member A (Epidermal growth factor receptor 5) (EGFR-5)
Gene Symbol CLEC14A; C14orf27; EGFR5; UNQ236/PRO269
Organism Homo sapiens (Human)
Length 490 aa
Isoforms No isoforms
Related PMIDs 24357059
Database Sources No database sources
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
1
Endothelial cells
Specificity: 1.000
1/2 (50.0%)
0
Jurkat T cells
Specificity: 0.000
0/25 (0.0%)
0
U937 cells
Specificity: 0.000
0/1 (0.0%)
0
DU145 cells
Specificity: 0.000
0/2 (0.0%)
0
HeLa cells
Specificity: 0.000
0/1 (0.0%)
0
LNCaP cells
Specificity: 0.000
0/46 (0.0%)
0
PC3 cells
Specificity: 0.000
0/4 (0.0%)
0
T cells
Specificity: 0.000
0/4 (0.0%)
0
HAP1 cells
Specificity: 0.000
0/10 (0.0%)
0
293T cells
Specificity: 0.000
0/10 (0.0%)
0
CEMx174 cells
Specificity: 0.000
0/3 (0.0%)
0
Prefrontal cortex
Specificity: 0.000
0/1 (0.0%)
0
Cerebral cortex
Specificity: 0.000
0/4 (0.0%)
0
Liver membrane
Specificity: 0.000
0/1 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MRPAFALCLL11WQALWPGPGG21GEHPTADRAG31CSASGACYSL41HHATMKRQAA
51-10051EEACILRGGA61LSTVRAGAEL71RAVLALLRAG81PGPGGGSKDL91LFWVALERRR
101-150101SHCTLENEPL111RGFSWLSSDP121GGLESDTLQW131VEEPQRSCTA141RRCAVLQATG
151-200151GVEPAGWKEM161RCHLRANGYL171CKYQFEVLCP181APRPGAASNL191SYRAPFQLHS
201-250201AALDFSPPGT211EVSALCRGQL221PISVTCIADE231IGARWDKLSG241DVLCPCPGRY
251-300251LRAGKCAELP261NCLDDLGGFA271CECATGFELG281KDGRSCVTSG291EGQPTLGGTG
301-350301VPTRRPPATA311TSPVPQRTWP321IRVDEKLGET331PLVPEQDNSV341TSIPEIPRWG
351-400351SQSTMSTLQM361SLQAESKATI371TPSGSVISKF381NSTTSSATPQ391AFDSSSAVVF
401-450401IFVSTAVVVL411VILTMTVLGL421VKLCFHESPS431SQPRKESMGP441PGLESDPEPA
451-490451ALGSSSAHCT461NNGVKVGDCD471LRDRAEGALL481AESPLGSSDA
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
8 Prediction (Low) - -
54 Prediction (Medium) - -
103 Prediction (Medium) - -
138 Prediction (Low) - -
216 Prediction (Low) - -
226 Prediction (Low) - -
244 Prediction (Medium) - -
246 Prediction (Medium) - -
271 Prediction (Low) - -
273 Prediction (Medium) - -
286 Prediction (Medium) - -
Conservation Scores
PhyloP
PhastCons
TCGA Cysteine Mutation Information

Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.

Position Amino Acid Change Frequency Type Function Cancer Type
93 W → C 0.001887 SNP Missense Mutation UCEC
137 S → C 0.001014 SNP Missense Mutation BRCA
143 C → F 0.001764 SNP Missense Mutation LUAD
143 C → C 0.002506 SNP Silent COAD
143 C → C 0.001887 SNP Silent UCEC
162 C → C 0.002506 SNP Silent COAD
165 R → C 0.002506 SNP Missense Mutation COAD
171 C → C 0.002033 SNP Silent LUSC
193 R → C 0.004283 SNP Missense Mutation SKCM
226 C → F 0.001969 SNP Missense Mutation HNSC
240 G → C 0.001969 SNP Missense Mutation HNSC
244 C → Y 0.001764 SNP Missense Mutation LUAD
244 C → C 0.007299 SNP Silent READ
246 C → C 0.002506 SNP Silent COAD
252 R → C 0.002020 SNP Missense Mutation PRAD
256 C → C 0.001887 SNP Silent UCEC
273 C → Y 0.002747 SNP Missense Mutation LIHC
305 R → C 0.002288 SNP Missense Mutation STAD
305 R → C 0.005618 SNP Missense Mutation PAAD
442 G → C 0.002033 SNP Missense Mutation LUSC