Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q86VU5 | COMTD1 | Catechol O-methyltransferase domain-containing protein 1 … | Homo sapiens (Human) | 262 aa |
Protein Details: Q86VU5 (COMTD1)
Protein Information
| Accession | Q86VU5 |
|---|---|
| Protein Names | Catechol O-methyltransferase domain-containing protein 1 (EC 2.1.1.-) |
| Gene Symbol | COMTD1 |
| Organism | Homo sapiens (Human) |
| Length | 262 aa |
| Isoforms | No isoforms |
| Related PMIDs | 26111759 31251020 33636221 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTQPVPRLSV11PAALALGSAA21LGAAFATGLF31LGRRCPPWRG41RREQCLLPPE
51-10051DSRLWQYLLS61RSMREHPALR71SLRLLTLEQP81QGDSMMTCEQ91AQLLANLARL
101-150101IQAKKALDLG111TFTGYSALAL121ALALPADGRV131VTCEVDAQPP141ELGRPLWRQA
151-200151EAEHKIDLRL161KPALETLDEL171LAAGEAGTFD181VAVVDADKEN191CSAYYERCLQ
201-250201LLRPGGILAV211LRVLWRGKVL221QPPKGDVAAE231CVRNLNERIR241RDVRVYISLL
251-262251PLGDGLTLAF261KI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 35 | SWISSPALM DBPTM CYSMODDB | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.83
Deep-Palm: 0.98
|
| 45 | - |
HeLa
(37611173)
| - |
GPS-Palm: 0.73
Deep-Palm: 0.93
|
|
| 88 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.98
|
|
| 133 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.98
|
|
| 191 | - | - | - |
Deep-Palm: 0.94
|
|
| 198 | - | - |
LNCaP
(31251020)
|
Deep-Palm: 0.96
|
|
| 231 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.87
Deep-Palm: 0.97
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.500
3
LNCaP
Specificity: 0.429
3/3 (100.0%)
2
Primary T cell
Specificity: 0.286
2/2 (100.0%)
1
heart
Specificity: 0.143
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 0.143
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.