Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q86W47 | KCNMB4 | Calcium-activated potassium channel subunit beta-4 … | Homo sapiens (Human) | 210 aa |
Protein Details: Q86W47 (KCNMB4)
Protein Information
| Accession | Q86W47 |
|---|---|
| Protein Names | Calcium-activated potassium channel subunit beta-4 (BK channel subunit beta-4) (BKbeta4) (Hbeta4) (Calcium-activated potassium channel, subfamily M subunit beta-4) (Charybdotoxin receptor subunit beta-4) (K(VCA)beta-4) (Maxi K channel subunit beta-4) (Slo-beta-4) |
| Gene Symbol | KCNMB4 |
| Organism | Homo sapiens (Human) |
| Length | 210 aa |
| Isoforms | No isoforms |
| Related PMIDs | No related PMIDs |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MAKLRVAYEY11TEAEDKSIRL21GLFLIISGVV31SLFIFGFCWL41SPALQDLQAT
51-10051EANCTVLSVQ61QIGEVFECTF71TCGADCRGTS81QYPCVQVYVN91NSESNSRALL
101-150101HSDEHQLLTN111PKCSYIPPCK121RENQKNLESV131MNWQQYWKDE141IGSQPFTCYF
151-200151NQHQRPDDVL161LHRTHDEIVL171LHCFLWPLVT181FVVGVLIVVL191TICAKSLAVK
201-210201AEAMKKRKFS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 38 | Potassium channel, calcium-activated, BK, beta subunit | - | - |
Deep-Palm: 0.72
|
|
| 54 | - | - | - |
GPS-Palm: 0.75
Deep-Palm: 0.78
|
|
| 68 | - | - | - |
Deep-Palm: 0.06
|
|
| 72 | - | - | - |
Deep-Palm: 0.09
|
|
| 76 | - | - | - |
Deep-Palm: 0.03
|
|
| 84 | - | - | - |
Deep-Palm: 0.15
|
|
| 113 | - | - | - |
Deep-Palm: 0.73
|
|
| 119 | - | - | - |
GPS-Palm: 0.68
Deep-Palm: 0.18
|
|
| 148 | - | - | - |
Deep-Palm: 0.10
|
|
| 173 | - | - | - |
Deep-Palm: 0.32
|
|
| 193 | DBPTM SWISSPALM | Calcium-activated potassium channel beta subunit | - | - |
GPS-Palm: 0.94
Deep-Palm: 0.96
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 39 | W → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 76 | C → Y | 0.005618 | SNP | Missense Mutation | PAAD |
| 146 | F → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 149 | Y → C | 0.002427 | SNP | Missense Mutation | BLCA |
| 163 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 163 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 207 | R → C | 0.001969 | SNP | Missense Mutation | HNSC |
| 207 | R → C | 0.001887 | SNP | Missense Mutation | UCEC |