Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q86YZ4 | SLC26A6 | Solute carrier family 26, member … | Homo sapiens (Human) | 753 aa |
Protein Details: Q86YZ4 (SLC26A6)
Protein Information
| Accession | Q86YZ4 |
|---|---|
| Protein Names | Solute carrier family 26, member 6 |
| Gene Symbol | SLC26A6 |
| Organism | Homo sapiens (Human) |
| Length | 753 aa |
| Isoforms | No isoforms |
| Related PMIDs | 31251020 (mass) 32651440 (mass) 36430497 (mass) |
| Database Sources | dbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MGLADASGPR11DTQALLSATQ21AMDLRRRDYH31MERPLLNQEH41LEELGRWGSA
51-10051PRTHQWRTWL61QCSRARAYAL71LLQHLPVLVW81LPRYPVRDWL91LGDLLSGLSV
101-150101AIMQLPQDLL111SRLHCYHSTL121GLAYALLAGL131PPVFGLYSSF141YPVFIYFLFG
151-200151TSRHISVGTF161AVMSVMVGSV171TESLAPQALN181DSMINETARD191AARVQVASTL
201-250201SVLVGLFQVG211LGLIHFGFVV221TYLSEPLVRG231YTTAAAVQVF241VSQLKYVFGL
251-300251HLSSHSGPLS261LIYTVLEVCW271KLPQSKVGTV281VTAAVAGVVL291VVVKLLNDKL
301-350301QQQLPMPIPG311ELLTLIGATG321ISYGMGLKHR331FEVDVVGNIP341AGLVPPVAPN
351-400351TQLFSKLVGS361AFTIAVVGFA371IAISLGKIFA381LRHGYRVDSN391QELVALGLSN
401-450401LIGGIFQCFP411VSCSMSRSLV421QESTGGNSQV431AGAISSLFIL441LIIVKLGELF
451-500451HDLPKAVLAA461IIIVNLKGML471RQLSDMRSLW481KANRADLLIW491LVTFTATILL
501-550501NLDLGLVVAV511IFSLLLVVVR521TQMPHYSVLG531QVPDTDIYRD541VAEYSEAKEV
551-600551RGVKVFRSSA561TVYFANAEFY571SDALKQRCGV581DVDFLISQKK591KLLKKQEQLK
601-650601LKQLQKEEKL611RKQAGPLLSA621CLAPQQVSSG631DKMEDATANG641QEDSKAPDGS
651-700651TLKALGLPQP661DFHSLILDLG671ALSFVDTVCL681KSLKNIFHDF691REIEVEVYMA
701-750701ACHSPVVSQL711EAGHFFDASI721TKKHLFASVH731DAVTFALQHP741RPVPDSPVSV
751-753751TRL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 62 | DBPTM SWISSPALM | - |
HeLa
(29575903)
| - |
GPS-Palm: 0.76
Deep-Palm: 0.93
|
| 115 | - | - | - |
Deep-Palm: 0.95
|
|
| 269 | - | - | - |
GPS-Palm: 0.85
Deep-Palm: 0.96
|
|
| 408 | - | - | - |
GPS-Palm: 0.73
Deep-Palm: 0.86
|
|
| 413 | - | - | - |
GPS-Palm: 0.74
Deep-Palm: 0.59
|
|
| 578 | - | - |
LNCaP
(31251020)
|
GPS-Palm: 0.65
Deep-Palm: 0.83
|
|
| 621 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.98
|
|
| 679 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.93
|
|
| 702 | - | - | - |
Deep-Palm: 0.28
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
LNCaP cells (Mass)
Specificity: 1.000
1/4 (25.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
TCGA Cysteine Mutation Information
Note: Mutations indicate amino acid changes that may create potential palmitoylation sites.
| Position | Amino Acid Change | Frequency | Type | Function | Cancer Type |
|---|---|---|---|---|---|
| 87 | R → C | 0.001764 | SNP | Missense Mutation | LUAD |
| 97 | G → C | 0.001887 | SNP | Missense Mutation | UCEC |
| 531 | Y → C | 0.002506 | SNP | Missense Mutation | COAD |
| 544 | R → C | 0.002033 | SNP | Missense Mutation | LUSC |
| 544 | R → C | 0.002141 | SNP | Missense Mutation | SKCM |
| 683 | T → _V684insHYSECACEGGF | 0.005435 | INS | In Frame Ins | ESCA |
| 400* | C → ? | 0.002288 | SNP | Nonsense Mutation | STAD |