Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8BGQ7 Aars1 Alanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) … Mus musculus (Mouse) 968 aa

Protein Details: Q8BGQ7 (Aars1)

Protein Information
AccessionQ8BGQ7
Protein NamesAlanine--tRNA ligase, cytoplasmic (EC 6.1.1.7) (Alanyl-tRNA synthetase) (AlaRS) (Protein lactyltransferase AARS1) (EC 6.-.-.-) (Protein sticky) (Sti)
Gene SymbolAars1
OrganismMus musculus (Mouse)
Length968 aa
IsoformsNo isoforms
Related PMIDs 28526873 35358180 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MDATLTAREI11RERFINFFRR21NEHTYVHSSA31TIPLDDPTLL41FANAGMNQFK
51-10051PIFLNTIDPS61HPMAKLSRAA71NTQKCIRAGG81KHNDLDDVGK91DVYHHTFFEM
101-150101LGSWSFGDYF111KELACKMALE121LLTQEFGIPV131ERLYVTYFGG141DEAAGLEPDL
151-200151ECRQIWQNLG161LDEARILPGN171MKDNFWEMGD181TGPCGPCSEI191HYDRIGGRDA
201-250201AHLVNQDDPN211VLEIWNLVFI221QYNRESDGVL231KPLPKKSIDT241GMGLERLVSV
251-300251LQNKMSNYDT261DLFMPYFEAI271QKGTGARPYT281GKVGAEDADG291IDMAYRVLAD
301-350301HARTITVALA311DGGRPDNTGR321GYVLRRILRR331AVRYSHEKLN341ASRGFFATLV
351-400351DVVVQSLGDA361FPELKKDPEM371VKDIINEEEV381QFLKTLSRGR391RILDRKIQSL
401-450401GDCKTIPGDT411AWLLYDTYGF421PVDLTGLIAE431EKGLVVDMNG441FEEERRLAQL
451-500451KSQGKGAGDE461DLIMLDIYAI471EELRAKGLEA481TDDSPKYNYQ491SDSSGSYVFE
501-550501CTVATVLALR511REKMFVDEVV521TGQECGVVLD531KTCFYAEQGG541QIYDEGYLVK
551-600551VDDSSEDKTE561FTVKNAQVRG571GYVLHIGTIY581GNLKVGDQVR591LFIDEPRRRP
601-650601VMSNHTATHI611LNFALRSVLG621EADQKGSLVA631PDRLRFDFTA641KGAMSTQQIK
651-700651KAEEIVNGMI661EAAKPVYTQD671CPLAAAKAIQ681GLRAVFDETY691PDPVRVVSIG
701-750701VPVSELLDDP711CGPAGSLTSV721EFCGGTHLRN731SSHAGAFVIV741TEEAIAKGIR
751-800751RIVAVTGAEA761QKALRKSETL771KKSLSAMEAK781VKAQTAPNKD791VQREIADLGE
801-850801ALATAVIPQW811QKDEQRETLK821SLKKVMDDLD831RASKADVQKR841VLEKTKQLID
851-900851SNPNQPLVIL861EMESGASAKA871LNEALKLFKT881HSPQTSAMLF891TVDNEAGKIT
901-950901CLCQVPQNAA911NRGLKASEWV921QQVSGLMDGK931GGGKDMSAQA941TGKNVGCLQE
951-968951ALQLATSFAQ961LRLGDVKN
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
75 - - -
Deep-Palm: 0.91
115 - - -
Deep-Palm: 0.95
152 - -
Brain (35358180)
Deep-Palm: 0.91
184 - - -
Deep-Palm: 0.07
187 - - -
Deep-Palm: 0.09
403 - - -
Deep-Palm: 0.94
501 - - -
Deep-Palm: 0.81
525 - - -
Deep-Palm: 0.74
533 - - -
Deep-Palm: 0.66
671 - -
Brain (35358180)
Deep-Palm: 0.97
711 - - -
Deep-Palm: 0.98
723 - - -
Deep-Palm: 0.95
901 -
brain (39008777)
MLE (39008777)
-
Deep-Palm: 0.88
903 -
brain (39008777)
MLE (39008777)
-
Deep-Palm: 0.88
947 SWISSPALM DBPTM CYSMODDB DHHA1 domain
Liver (28526873)
Brain (35358180)
Deep-Palm: 0.96
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.800
4
Liver
Specificity: 0.235
4/4 (100.0%)
1
Brain
Specificity: 0.059
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
12
Brain tissue (Mass)
Specificity: 0.706
12/56 (21.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine