Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8BH04 Pck2 Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) … Mus musculus (Mouse) 640 aa

Protein Details: Q8BH04 (Pck2)

Protein Information
AccessionQ8BH04
Protein NamesPhosphoenolpyruvate carboxykinase [GTP], mitochondrial (PEPCK-M) (EC 4.1.1.32) (Serine/threonine-protein kinase PCK2) (EC 2.7.11.-)
Gene SymbolPck2
OrganismMus musculus (Mouse)
Length640 aa
IsoformsNo isoforms
Related PMIDs 28526873 29660268 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MAAMYLPGLR11LSRHGLRPWC21WSPCRSIQTL31HVLSGDMSQL41PAGVRDFVAR
51-10051SAHLCQPEGI61HICDGTEAEN71TAILALLEEQ81GLIRKLPKYK91NCWLARTDPK
101-150101DVARVESKTV111IVTPSQRDTV121PLLAGGARGQ131LGNWMSPDEF141QRAVDERFPG
151-200151CMQGRIMYVL161PFSMGPVGSP171LSRIGVQLTD181SAYVVASMRI191MTRLGTPVLQ
201-250201ALGDGDFIKC211LHSVGQPLTG221HGDPVGQWPC231NPEKTLIGHV241PDQREIVSFG
251-300251SGYGGNSLLG261KKCFALRIAS271RLARDEGWLA281EHMLILGITN291PAGKKRYVAA
301-350301AFPSACGKTN311LAMMRPALPG321WKVECVGDDI331AWMRFDSEGQ341LRAINPENGF
351-400351FGVAPGTSAA361TNPNAMATIQ371SNTLFTNVAE381TSDGGVYWEG391IDQPLPPGVT
401-450401ITSWLGKPWK411PGDKEPCAHP421NSRFCVPARQ431CPIMDPAWEA441PEGVPIDAII
451-500451FGGRRPKGVP461LVYEAFNWRH471GVFVGSAMRS481ESTAAAEHKG491KTIMHDPFAM
501-550501RPFFGYNFGR511YLEHWLSMEG521QKGARLPRIF531HVNWFRRDEA541GRFLWPGFGE
551-600551NARVLDWICR561RLEGEDSAQE571TPIGLVPKEG581ALDLSGLSAV591DTSQLFSIPK
601-640601DFWEQEVRDI611RGYLTEQVNQ621DLPKEVLAEL631EALEGRVQKM
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
20 - - -
Deep-Palm: 0.92
24 - - -
Deep-Palm: 0.74
55 - - -
Deep-Palm: 0.91
63 - - -
Deep-Palm: 0.88
92 - - -
GPS-Palm: 0.92
Deep-Palm: 0.97
151 - - -
Deep-Palm: 0.73
210 - - -
Deep-Palm: 0.91
230 - - -
Deep-Palm: 0.43
263 - - -
Deep-Palm: 0.97
306 SWISSPALM DBPTM CYSMODDB Phosphoenolpyruvate carboxykinase C-terminal P-loop domain
Liver (28526873)
-
GPS-Palm: 0.94
Deep-Palm: 0.93
325 - -
Brain (35358180)
Deep-Palm: 0.68
417 - - -
Deep-Palm: 0.15
425 - - -
Deep-Palm: 0.14
431 - - -
Deep-Palm: 0.10
559 - - -
Deep-Palm: 0.94
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.667
2
Brain
Specificity: 0.333
2/2 (100.0%)
1
Liver
Specificity: 0.167
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.500
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine