Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8BIJ6 Iars2 Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) … Mus musculus (Mouse) 1012 aa

Protein Details: Q8BIJ6 (Iars2)

Protein Information
Accession Q8BIJ6
Protein Names Isoleucine--tRNA ligase, mitochondrial (EC 6.1.1.5) (Isoleucyl-tRNA synthetase) (IleRS)
Gene Symbol Iars2
Organism Mus musculus (Mouse)
Length 1012 aa
Isoforms No isoforms
Related PMIDs 28526873 29660268 29733200 31772009 34200797 35477839 37925639
Database Sources CysModDB dbPTM SwissPalm
These studies detected palmitoylation of this protein in the samples.
Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.633
Bubble Size: Positive Samples Count Color Intensity: Positive Ratio
19
Liver tissue
Specificity: 0.633
19/19 (100.0%)
6
Brain tissue
Specificity: 0.200
6/12 (50.0%)
3
Neural Stem Cells
Specificity: 0.100
3/3 (100.0%)
2
Testis
Specificity: 0.067
2/2 (100.0%)
0
Macrophage Raw 264.7
Specificity: 0.000
0/2 (0.0%)
0
Liver membrane
Specificity: 0.000
0/6 (0.0%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples. Bars are grouped by tissue/cell line for easy comparison.
Protein Sequence
Single Types:
Experimental Database High Prediction Medium Prediction Low Prediction
Combined Types:
All Three Exp + DB Exp + High Pred Exp + Med Pred Exp + Low Pred DB + High Pred DB + Med Pred DB + Low Pred Cysteine
1-501MHWGLCPRGP11GAAAVAAAGS21FWGPARLPSR31LGCLGMTRRL41VVRSVAGADS
51-10051PQSSSKGGRY61RDTVLLPQTS71FPMKLLGRQQ81SDMELEIQQK91CGFSELYSWQ
101-150101RERKVKTEFC111LHDGPPYANG121DPHVGHALNK131ILKDIANRFH141MMRGSKVHFV
151-200151PGWDCHGLPI161ETKVLSELGV171DAQSLSAMEI181REKARSFAQA191AIEKQKSAFV
201-250201RWGVMADWNN211CYYTFDPKYE221AKQLRVFYQM231YEKGLVYRSY241KPVYWSPSSR
251-300251TALAEAELEY261NPEHVSRSIY271VRFPLLRPPP281KLESLTDASS291PVSVLVWTTQ
301-350301PWTIPANQAI311CYMPEAKYAV321VKCSASGHLY331ILAEDKIAPV341ASALETTFDV
351-400351VAAFSGVDLE361GGTCSHPLTP371DKVSPLLPAT381HVTMAKGTGL391VHTAPAHGME
401-450401DYSVASQHSL411PMDCLVDEGG421MFTDAAGPEL431QNKAVLKEGT441DVVIKMLQAT
451-500451KNVLKEENIV461HSYPCDWRTK471TPVLIRASKQ481WFVNITDIKA491AAKESLKTVK
501-550501FIPGAALNSM511TDMLDRRPYW521CISRQRVWGV531PIPVFHHKTK541DEYLINSQTT
551-600551EHIIKLVEQH561GSDVWWTLPA571EQLLPAEVLA581QAGGPGALEY591APGQDILDIW
601-650601FDSGTSWSCV611LQDTQQRADL621YLEGKDQLGG631WFQSSLLTSV641ATRSKAPFRT
651-700651VMVHGFTLGE661KGEKMSKSLG671NVINPDTIIS681GGKDHSKEPP691YGADILRWWI
701-750701AESNVFTEVT711IGPSVLSAAR721DDISKLRNTL731RFLLGNLTGF741NPETDSVPVK
751-800751NMYVIDQYML761HLIQDFATKI771TDSYKQYDFG781KVVRLLKAFY791TRELSSFYFS
801-850801IVKDRLYCEN811EKDPKRRSCQ821TALAEILDVL831VRAFAPILPH841LAEEVFQHIP
851-900851YVTEPKSVFR861TGWINTSSIW871KKPGLEEAVE881SACAMRDSFL891GSIPGKNAAE
901-950901YEVIIVIEPG911LLFEIMEMLQ921AEETSSTSQL931NELMMASQTT941LLAQEPRERT
951-1000951AGDIELTGTF961VINLEGGDIR971EESSYKVIVV981PTAREKCPRC991WKHTSETADA
1001-10121001LCPRCAEVIG1011AK
Palmitoylation Sites Details
Position Sources Domains Experimental PMIDs
6 Prediction (High) - -
33 Prediction (High) - -
155 Experimental tRNA synthetases class I (I L M and V) 34200797
819 Experimental CYSMODDB SWISSPALM DBPTM Anticodon-binding domain of tRNA ligase 28526873
1002 Experimental Zinc finger found in FPG and IleRS 34200797
1005 Experimental Zinc finger found in FPG and IleRS 34200797
Conservation Scores
PhyloP
PhastCons