Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8BLE7 Slc17a6 Vesicular glutamate transporter 2 (VGluT2) … Mus musculus (Mouse) 582 aa

Protein Details: Q8BLE7 (Slc17a6)

Protein Information
AccessionQ8BLE7
Protein NamesVesicular glutamate transporter 2 (VGluT2) (Differentiation-associated BNPI) (Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter) (Solute carrier family 17 member 6)
Gene SymbolSlc17a6
OrganismMus musculus (Mouse)
Length582 aa
IsoformsNo isoforms
Related PMIDs 29733200 34200797 35358180 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass)
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501MESVKQRILA11PGKEGIKNFA21GKSLGQIYRV31LEKKQDNRET41IELTEDGKPL
51-10051EVPEKKAPLC61DCTCFGLPRR71YIIAIMSGLG81FCISFGIRCN91LGVAIVDMVN
101-150101NSTIHRGGKV111IKEKAKFNWD121PETVGMIHGS131FFWGYIITQI141PGGYIASRLA
151-200151ANRVFGAAIL161LTSTLNMLIP171SAARVHYGCV181IFVRILQGLV191EGVTYPACHG
201-250201IWSKWAPPLE211RSRLATTSFC221GSYAGAVIAM231PLAGILVQYT241GWSSVFYVYG
251-300251SFGMVWYMFW261LLVSYESPAK271HPTITDEERR281YIEESIGESA291NLLGAMEKFK
301-350301TPWRKFFTSM311PVYAIIVANF321CRSWTFYLLL331ISQPAYFEEV341FGFEISKVGM
351-400351LSAVPHLVMT361IIVPIGGQIA371DFLRSKQILS381TTTVRKIMNC391GGFGMEATLL
401-450401LVVGYSHTRG411VAISFLVLAV421GFSGFAISGF431NVNHLDIAPR441YASILMGISD
451-500451GVGTLSGMVC461PIIVGAMTKN471KSREEWQYVF481LIAALVHYGG491VIFYALFASG
501-550501EKQPWADPEE511TSEEKCGFIH521EDELDEETGD531ITQNYINYGT541TKSYGATSQE
551-582551NGGWPNGWEK561KEEFVQEGAQ571DAYTYKDRDD581YS
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
60 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.93
Deep-Palm: 0.91
62 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.95
Deep-Palm: 0.91
64 SWISSPALM DBPTM CYSMODDB -
Forebrain (28680068)
brain (39008777)
Brain (35358180)
GPS-Palm: 0.95
Deep-Palm: 0.88
82 - - -
Deep-Palm: 0.44
89 - - -
Deep-Palm: 0.10
179 - -
Brain (35358180)
GPS-Palm: 0.91
Deep-Palm: 0.67
198 - -
Brain (35358180)
Brain (31311849)
Deep-Palm: 0.67
220 - - -
Deep-Palm: 0.74
321 - - -
Deep-Palm: 0.04
390 - - -
Deep-Palm: 0.92
460 - - -
Deep-Palm: 0.64
516 -
Brain (34200797)
-
Deep-Palm: 0.40
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
4
Brain
Specificity: 0.143
4/4 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
24
Brain tissue (Mass)
Specificity: 0.857
24/56 (42.9%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine