Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8BLN5 | Lss | Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol … | Mus musculus (Mouse) | 733 aa |
Protein Details: Q8BLN5 (Lss)
Protein Information
| Accession | Q8BLN5 |
|---|---|
| Protein Names | Lanosterol synthase (EC 5.4.99.7) (2,3-epoxysqualene--lanosterol cyclase) (Oxidosqualene--lanosterol cyclase) (OSC) |
| Gene Symbol | Lss |
| Organism | Mus musculus (Mouse) |
| Length | 733 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29660268 34884899 35477839 37925639 |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MTEGTCLRRR11GGPYKTEPAT21DLTRWRLQNE31LGRQRWTYYQ41AEDDPGREQT
51-10051GLEAHSLGLD61TRSYFTDLPK71AQTAHEGALN81GVTFYAKLQA91EDGHWAGDYG
101-150101GPLFLLPGLL111ITCHISHISL121PAGYREEMVR131YLRSVQLPDG141GWGLHIEDKS
151-200151TVFGTALNYV161ALRILGIGPD171DPDLVRARNV181LHKKGGAVAI191PSWGKFWLAV
201-250201LNVYSWEGLN211TLFPEMWLFP221EWVPAHPSTL231WCHCRQVYLP241MSYCYATRLS
251-300251ASEDPLVQSL261RQELYVQDYA271SIDWPAQRNN281VSPDEMYTPH291SWLLHVVYGL
301-350301LNLYERFHST311SLRKWAVQML321YEHIAADDCF331TKCISIGPIS341KTINMLVRWS
351-400351VDGPSSPAFQ361EHVSRIKDYL371WLGLDGMKMQ381GTNGSQIWDT391SFAIQALLEA
401-450401GAHHRPEFLP411CLQKAHEFLR421LSQVPENCPD431YQKYYRHMRK441GGFSFSTLDC
451-500451GWIVADCTAE461GLKAVLLLQN471QCPSITEHIP481RERLCDAVDV491LLSLRNADGG
501-550501FATYEKKRGG511YLLELLNPSE521VFGDIMIDYT531YVECTSAVMQ541ALKHFHEHFP
551-600551DYRAAEVRET561LNQGLDFCRR571KQRADGSWEG581SWGVCFTYGT591WFGLEAFACM
601-650601GHTYQDGAAC611AEVAQACNFL621LSQQMADGGW631GEDFESCEQR641RYVQSARSQV
651-700651HSTCWALMGL661MAVRHPDITA671QERGIRCLLG681KQLPNGDWPQ691ENISGVFNKS
701-733701CAISYTSYRN711IFPIWALGRF721SNLYPDNTLA731GHI
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 6 | - | - | - |
GPS-Palm: 0.96
Deep-Palm: 0.05
|
|
| 113 | - | - | - |
Deep-Palm: 0.94
|
|
| 232 | - | - | - |
Deep-Palm: 0.04
|
|
| 234 | - | - | - |
Deep-Palm: 0.05
|
|
| 244 | - | - | - |
Deep-Palm: 0.18
|
|
| 329 | - | - | - |
Deep-Palm: 0.19
|
|
| 333 | - | - | - |
Deep-Palm: 0.29
|
|
| 411 | - | - | - |
Deep-Palm: 0.98
|
|
| 428 | - | - | - |
Deep-Palm: 0.57
|
|
| 450 | - | - | - |
Deep-Palm: 0.92
|
|
| 457 | - | - | - |
Deep-Palm: 0.96
|
|
| 472 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Liver
(34884899)
|
Deep-Palm: 0.97
|
| 485 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
| - |
Deep-Palm: 0.95
|
| 534 | - | - | - |
Deep-Palm: 0.09
|
|
| 568 | - | - | - |
GPS-Palm: 0.90
Deep-Palm: 0.96
|
|
| 585 | - | - | - |
Deep-Palm: 0.53
|
|
| 599 | - | - | - |
Deep-Palm: 0.25
|
|
| 610 | - | - | - |
Deep-Palm: 0.27
|
|
| 617 | - | - | - |
Deep-Palm: 0.50
|
|
| 637 | - | - | - |
Deep-Palm: 0.40
|
|
| 654 | - | - | - |
Deep-Palm: 0.44
|
|
| 677 | - | - | - |
Deep-Palm: 0.94
|
|
| 701 | SWISSPALM DBPTM CYSMODDB | Squalene-hopene cyclase C-terminal domain |
Liver
(28526873)
| - |
Deep-Palm: 0.41
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.625
5
Liver
Specificity: 0.625
5/5 (100.0%)
2
Testis
Specificity: 0.250
2/2 (100.0%)
1
Brain
Specificity: 0.125
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.