Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8BMF4 | Dlat | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate … | Mus musculus (Mouse) | 642 aa |
Protein Details: Q8BMF4 (Dlat)
Protein Information
| Accession | Q8BMF4 |
|---|---|
| Protein Names | Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (EC 2.3.1.12) (Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex) (Pyruvate dehydrogenase complex component E2) (PDC-E2) (PDCE2) |
| Gene Symbol | Dlat |
| Organism | Mus musculus (Mouse) |
| Length | 642 aa |
| Isoforms | No isoforms |
| Related PMIDs | 29733200 31311849 31772009 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | SwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MWRVCARRAR11SAVPRDGFRA21RWAALKEGPG31APCGSPRIGP41AAVRCGSGIP
51-10051RYGVRSLCGW61SSGSGTVPRN71RLLRQLLGSP81SRRSYSLPPH91QKVPLPSLSP
101-150101TMQAGTIARW111EKKEGEKISE121GDLIAEVETD131KATVGFESLE141ECYMAKILVP
151-200151EGTRDVPVGS161IICITVEKPQ171DIEAFKNYTL181DLAAAAAPQA191APAAAPAPAA
201-250201APAAPSASAP211GSSYPTHMQI221VLPALSPTMT231MGTVQRWEKK241VGEKLSEGDL
251-300251LAEIETDKAT261IGFEVQEEGY271LAKILVPEGT281RDVPLGAPLC291IIVEKQEDIA
301-350301AFADYRPTEV311TSLKPQAAPP321APPPVAAVPP331TPQPVAPTPS341AAPAGPKGRV
351-400351FVSPLAKKLA361AEKGIDLTQV371KGTGPEGRII381KKDIDSFVPS391KAAPAAAAAM
401-450401APPGPRVAPA411PAGVFTDIPI421SNIRRVIAQR431LMQSKQTIPH441YYLSVDVNMG
451-500451EVLLVRKELN461KMLEGKGKIS471VNDFIIKASA481LACLKVPEAN491SSWMDTVIRQ
501-550501NHVVDVSVAV511STPAGLITPI521VFNAHIKGLE531TIASDVVSLA541SKAREGKLQP
551-600551HEFQGGTFTI561SNLGMFGIKN571FSAIINPPQA581CILAIGASED591KLIPADNEKG
601-642601FDVASVMSVT611LSCDHRVVDG621AVGAQWLAEF631KKYLEKPITM641LL
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 5 | - | - | - |
GPS-Palm: 0.93
Deep-Palm: 0.05
|
|
| 33 | - | - | - |
Deep-Palm: 0.97
|
|
| 45 | - | - | - |
Deep-Palm: 0.88
|
|
| 58 | - | - | - |
Deep-Palm: 0.89
|
|
| 142 | - | - | - |
Deep-Palm: 0.92
|
|
| 163 | - |
Brain
(34200797)
|
Brain
(35358180)
|
GPS-Palm: 0.89
Deep-Palm: 0.97
|
|
| 290 | - |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.90
Deep-Palm: 0.93
|
|
| 483 | - | - |
Brain
(35358180)
Brain
(31311849)
|
GPS-Palm: 0.93
Deep-Palm: 0.91
|
|
| 581 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) |
Brain
(31311849)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.95
|
|
| 613 | - | - |
Brain
(35358180)
|
Deep-Palm: 0.87
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.385
5
Brain
Specificity: 0.106
5/5 (100.0%)
5
Liver
Specificity: 0.106
5/5 (100.0%)
2
Testis
Specificity: 0.043
2/2 (100.0%)
1
NSC
Specificity: 0.021
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
34
Brain tissue (Mass)
Specificity: 0.723
34/56 (60.7%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.