Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8BMS1 | Hadha | Trifunctional enzyme subunit alpha, mitochondrial … | Mus musculus (Mouse) | 763 aa |
Protein Details: Q8BMS1 (Hadha)
Protein Information
| Accession | Q8BMS1 |
|---|---|
| Protein Names | Trifunctional enzyme subunit alpha, mitochondrial (Monolysocardiolipin acyltransferase) (MLCL AT) (EC 2.3.1.-) (TP-alpha) [Includes: Long-chain enoyl-CoA hydratase (EC 4.2.1.17); Long chain 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211)] |
| Gene Symbol | Hadha |
| Organism | Mus musculus (Mouse) |
| Length | 763 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29575903 29733200 31311849 34200797 34884899 35358180 35477839 37925639 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MVASRAIGSL11SRFSAFRILR21SRGCICRSFT31TSSALLTRTH41INYGVKGDVA
51-10051VIRINSPNSK61VNTLNKEVQS71EFIEVMNEIW81ANDQIRSAVL91ISSKPGCFVA
101-150101GADINMLSSC111TTPQEATRIS121QEGQRMFEKL131EKSPKPVVAA141ISGSCLGGGL
151-200151ELAIACQYRI161ATKDRKTVLG171VPEVLLGILP181GAGGTQRLPK191MVGVPAAFDM
201-250201MLTGRNIRAD211RAKKMGLVDQ221LVEPLGPGIK231SPEERTIEYL241EEVAVNFAKG
251-300251LADRKVSAKQ261SKGLVEKLTT271YAMTVPFVRQ281QVYKTVEEKV291KKQTKGLYPA
301-350301PLKIIDAVKA311GLEQGSDAGY321LAESQKFGEL331ALTKESKALM341GLYNGQVLCK
351-400351KNKFGAPQKN361VQQLAILGAG371LMGAGIAQVS381VDKGLKTLLK391DTTVTGLGRG
401-450401QQQVFKGLND411KVKKKALTSF421ERDSIFSNLI431GQLDYKGFEK441ADMVIEAVFE
451-500451DLGVKHKVLK461EVESVTPEHC471IFASNTSALP481INQIAAVSKR491PEKVIGMHYF
501-550501SPVDKMQLLE511IITTDKTSKD521TTASAVAVGL531RQGKVIIVVK541DGPGFYTTRC
551-600551LAPMMSEVMR561ILQEGVDPKK571LDALTTGFGF581PVGAATLADE591VGVDVAQHVA
601-650601EDLGKAFGER611FGGGSVELLK621QMVSKGFLGR631KSGKGFYIYQ641EGSKNKSLNS
651-700651EMDNILANLR661LPAKPEVSSD671EDVQYRVITR681FVNEAVLCLQ691EGILATPAEG
701-750701DIGAVFGLGF711PPCLGGPFRF721VDLYGAQKVV731DRLRKYESAY741GTQFTPCQLL
751-763751LDHANNSSKK761FYQ
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 24 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.97
|
|
| 26 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.94
|
|
| 97 | - | - | - |
Deep-Palm: 0.95
|
|
| 110 | - | - | - |
Deep-Palm: 0.72
|
|
| 145 | - | - | - |
Deep-Palm: 0.98
|
|
| 156 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.98
|
|
| 349 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.96
|
| 470 | SWISSPALM DBPTM CYSMODDB | 3-hydroxyacyl-CoA dehydrogenase NAD binding domain |
Brain
(31311849)
Forebrain
(28680068)
brain
(39008777)
Liver
(28526873)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.93
|
| 550 | - | - | - |
Deep-Palm: 0.79
|
|
| 688 | - | - | - |
Deep-Palm: 0.97
|
|
| 713 | - | - | - |
Deep-Palm: 0.96
|
|
| 747 | SWISSPALM DBPTM CYSMODDB | - |
Liver
(28526873)
Brain
(31311849)
liver
(26165157)
|
Brain
(35358180)
Brain
(31311849)
|
Deep-Palm: 0.81
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.429
6
Liver
Specificity: 0.133
6/6 (100.0%)
5
Brain
Specificity: 0.111
5/5 (100.0%)
2
Testis
Specificity: 0.044
2/2 (100.0%)
1
Raw 264.7
Specificity: 0.022
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
31
Brain tissue (Mass)
Specificity: 0.689
31/56 (55.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.