Search Database

Select Protein (1 found)

UniProt ID Gene Symbol Protein Name Organism Length Action
Q8BU33 Hacl2 2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) … Mus musculus (Mouse) 632 aa

Protein Details: Q8BU33 (Hacl2)

Protein Information
AccessionQ8BU33
Protein Names2-hydroxyacyl-CoA lyase 2 (EC 4.1.2.-) (Acetolactate synthase-like protein) (IlvB-like protein)
Gene SymbolHacl2
OrganismMus musculus (Mouse)
Length632 aa
IsoformsNo isoforms
Related PMIDs 28526873 37925639
Database SourcesCysModDBdbPTMSwissPalm
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
1-501METSAAAASA11GGFFPSFLLL21AFGTLVAAVL31GVAHRLGLFY41QLMHKVDKTS
51-10051IRHGGESVAA61VLRAHGVRFV71FTLVGGHISP81LLVACEKLGI91RVVDTRHEVT
101-150101AVFAADAVAR111LTGTVGVAAV121TAGPGLTNTV131TAVKNAQVAQ141SPVLLLGGAA
151-200151STLLQKRGAL161QAIDQMSLFR171PLCKFCASVR181RVRDIVPTLR191TAIAAAQSGT
201-250201PGPVFVELPL211DVLYPYFMVE221KEMIPTKLPN231SLMGRVVVWY241LQNCLANLFV
251-300251GAWEPRPEGP261LPLDIPQASP271QQVQRCVEIL281SRAKRPLLVL291GSQALLPPTP
301-350301ANKLRAAVET311LGVPCFLGGM321SRGLLGRNHP331LHIRQNRSAA341LKKADVVVLA
351-400351GAVCDFRLSY361GRVLNRKSSI371IIVNRNRDDL381LLNSDIFWKP391QEAVQGDVGS
401-450401FMIKLVEGLQ411GQMWSSDWAE421ELRKADQQKE431QTYRDKALMP441VLQHLNPVWV
451-500451LQQVEETLPD461NALLVVDGGD471FVATAAYLVQ481PRGPLRWLDP491GAFGTLGVGA
501-550501GFALGAKLCQ511PEAEVWCLFG521DGAFGYSLIE531FDTFVRHKVP541VIALVGNDAG
551-600551WTQISREQVP561RLGSDVACSL571AYTDYHKAAM581GLGAQGLILS591RDNKDQVVKV
601-632601LREGQQLCQD611GHAVVVNILI621GRTDFRDGSI631SV
Palmitoylation Sites Details
Position Database Domains Literature (PMID/Cell-Tissue) Mass(PMID/Cell-Tissue) Prediction Scores
85 - - -
Deep-Palm: 0.98
173 - - -
GPS-Palm: 0.96
Deep-Palm: 0.83
176 - - -
GPS-Palm: 0.97
Deep-Palm: 0.77
244 - - -
Deep-Palm: 0.80
276 - - -
Deep-Palm: 0.98
315 SWISSPALM DBPTM CYSMODDB -
Liver (28526873)
-
Deep-Palm: 0.98
354 - - -
Deep-Palm: 0.98
509 - - -
Deep-Palm: 0.97
517 - - -
Deep-Palm: 0.94
568 - - -
Deep-Palm: 0.95
608 - - -
Deep-Palm: 0.91
Score Interpretation:
GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
2
Liver
Specificity: 1.000
2/2 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 0.000
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID). Blue bars: Literature data, Orange bars: Mass Spectrometry data. The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.
Conservation score for cysteine
PhyloP for Cysteine
PhastCons Conservation Scores for Cysteine