Search Database
Select Protein (1 found)
| UniProt ID | Gene Symbol | Protein Name | Organism | Length | Action |
|---|---|---|---|---|---|
| Q8BUN5 | Smad3 | SMAD family member 3 (SMAD … | Mus musculus (Mouse) | 425 aa |
Protein Details: Q8BUN5 (Smad3)
Protein Information
| Accession | Q8BUN5 |
|---|---|
| Protein Names | SMAD family member 3 (SMAD 3) (Mothers against decapentaplegic homolog 3) (MAD homolog 3) (Mad3) (Mothers against DPP homolog 3) (mMad3) |
| Gene Symbol | Smad3 |
| Organism | Mus musculus (Mouse) |
| Length | 425 aa |
| Isoforms | No isoforms |
| Related PMIDs | 28526873 29217618 (mass) 31311849 (mass) 31772009 (mass) 34884899 (mass) 35358180 (mass) 37925639 (mass) |
| Database Sources | CysModDBdbPTMSwissPalm |
These studies detected palmitoylation of this protein in the samples.
Protein Sequence
Types:
Experimental Database High Prediction Non-palmitylated Cys
Experimental Database High Prediction Non-palmitylated Cys
1-501MSSILPFTPP11IVKRLLGWKK21GEQNGQEEKW31CEKAVKSLVK41KLKKTGQLDE
51-10051LEKAITTQNV61NTKCITIPRS71LDGRLQVSHR81KGLPHVIYCR91LWRWPDLHSH
101-150101HELRAMELCE111FAFNMKKDEV121CVNPYHYQRV131ETPVLPPVLV141PRHTEIPAEF
151-200151PPLDDYSHSI161PENTNFPAGI171EPQSNIPETP181PPGYLSEDGE191TSDHQMNHSM
201-250201DAGSPNLSPN211PMSPAHNNLD221LQPVTYCEPA231FWCSISYYEL241NQRVGETFHA
251-300251SQPSMTVDGF261TDPSNSERFC271LGLLSNVNRN281AAVELTRRHI291GRGVRLYYIG
301-350301GEVFAECLSD311SAIFVQSPNC321NQRYGWHPAT331VCKIPPGCNL341KIFNNQEFAA
351-400351LLAQSVNQGF361EAVYQLTRMC371TIRMSFVKGW381GAEYRRQTVT391STPCWIELHL
401-425401NGPLQWLDKV411LTQMGSPSIR421CSSVS
Palmitoylation Sites Details
| Position | Database | Domains | Literature (PMID/Cell-Tissue) | Mass(PMID/Cell-Tissue) | Prediction Scores |
|---|---|---|---|---|---|
| 31 | MAD homology, MH1 SMAD MH1 domain superfamily Dwarfin | - | - |
Deep-Palm: 0.95
|
|
| 64 | - | - | - |
Deep-Palm: 0.95
|
|
| 89 | - | - | - |
Deep-Palm: 0.25
|
|
| 109 | - | - | - |
Deep-Palm: 0.11
|
|
| 121 | - | - | - |
Deep-Palm: 0.06
|
|
| 227 | - | - | - |
Deep-Palm: 0.06
|
|
| 233 | - | - | - |
Deep-Palm: 0.17
|
|
| 270 | SWISSPALM DBPTM CYSMODDB | MH2 domain |
Liver
(28526873)
|
Brain
(35358180)
|
Deep-Palm: 0.92
|
| 307 | - | - | - |
Deep-Palm: 0.11
|
|
| 320 | - | - | - |
Deep-Palm: 0.03
|
|
| 332 | - | - | - |
Deep-Palm: 0.05
|
|
| 338 | - | - | - |
Deep-Palm: 0.35
|
|
| 370 | - | - | - |
Deep-Palm: 0.53
|
|
| 394 | - | - | - |
Deep-Palm: 0.48
|
|
| 421 | - | - | - |
GPS-Palm: 0.91
Deep-Palm: 0.02
|
Score Interpretation:
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
• GPS-Palm: Thresholds - High (≥0.8920), Medium (≥0.7766), Low (≥0.6484), Very Low (<0.6484)
• Deep-Palm: Higher score indicates higher probability of palmitoylation (High ≥0.9)
Tissue/Cell Line Expression
Literature Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
1
Liver
Specificity: 0.250
1/1 (100.0%)
Mass Spectrometry Data - Tissue/Cell Line Expression
Tissue Specificity Index (TSI): 1.000
3
Brain tissue (Mass)
Specificity: 0.750
3/56 (5.4%)
Palmitoylation Distribution by Study and Tissue/Cell Line
Chart Explanation: Each bar represents a study (PMID).
Blue bars: Literature data, Orange bars: Mass Spectrometry data.
The colored bottom segment shows palmitoylated samples, while the gray top segment shows non-palmitoylated samples.